Pravachol
Pravachol Brand names, Pravachol Analogs
Pravachol Brand Names Mixture
- No information avaliable
Pravachol Chemical_Formula
C23H36O7
Pravachol RX_link
http://www.rxlist.com/cgi/generic/pravast.htm
Pravachol fda sheet
Pravachol msds (material safety sheet)
Pravachol Synthesis Reference
A. Terahara, M.Tanaka, U.S. Pat. 4,346,227(1982)
Pravachol Molecular Weight
424.528 g/mol
Pravachol Melting Point
326oC
Pravachol H2O Solubility
2464mg/L
Pravachol State
Solid
Pravachol LogP
2.613
Pravachol Dosage Forms
Tablet
Pravachol Indication
For the treatment of hypercholesterolemia to reduce the risk of myocardial infarction.
Pravachol Pharmacology
Pravastatin, an antilipemic agent, is used to treat primary hypercholesterolemia. Unlike lovastatin and simvastatin, pravastatin is relatively hydrophilic and does not require hydrolysis for activation.
Pravachol Absorption
Average oral absorption of pravastatin is 34% and absolute bioavailability is 17%.
Pravachol side effects and Toxicity
Rhabdomyolysis; LD50=mg/kg (orally in rat)
Pravachol Patient Information
Patients should be advised to report promptly unexplained muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever.
Pravachol Organisms Affected
Humans and other mammals
