Elisor
Elisor Brand names, Elisor Analogs
Elisor Brand Names Mixture
- No information avaliable
Elisor Chemical_Formula
C23H36O7
Elisor RX_link
http://www.rxlist.com/cgi/generic/pravast.htm
Elisor fda sheet
Elisor msds (material safety sheet)
Elisor Synthesis Reference
A. Terahara, M.Tanaka, U.S. Pat. 4,346,227(1982)
Elisor Molecular Weight
424.528 g/mol
Elisor Melting Point
326oC
Elisor H2O Solubility
2464mg/L
Elisor State
Solid
Elisor LogP
2.613
Elisor Dosage Forms
Tablet
Elisor Indication
For the treatment of hypercholesterolemia to reduce the risk of myocardial infarction.
Elisor Pharmacology
Pravastatin, an antilipemic agent, is used to treat primary hypercholesterolemia. Unlike lovastatin and simvastatin, pravastatin is relatively hydrophilic and does not require hydrolysis for activation.
Elisor Absorption
Average oral absorption of pravastatin is 34% and absolute bioavailability is 17%.
Elisor side effects and Toxicity
Rhabdomyolysis; LD50=mg/kg (orally in rat)
Elisor Patient Information
Patients should be advised to report promptly unexplained muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever.
Elisor Organisms Affected
Humans and other mammals
