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Compactin Brand names, Compactin Analogs

Compactin Brand Names Mixture

  • No information avaliable

Compactin Chemical_Formula


Compactin RX_link

Compactin fda sheet

Compactin FDA

Compactin msds (material safety sheet)

Compactin Synthesis Reference

A. Terahara, M.Tanaka, U.S. Pat. 4,346,227(1982)

Compactin Molecular Weight

424.528 g/mol

Compactin Melting Point


Compactin H2O Solubility


Compactin State


Compactin LogP


Compactin Dosage Forms


Compactin Indication

For the treatment of hypercholesterolemia to reduce the risk of myocardial infarction.

Compactin Pharmacology

Pravastatin, an antilipemic agent, is used to treat primary hypercholesterolemia. Unlike lovastatin and simvastatin, pravastatin is relatively hydrophilic and does not require hydrolysis for activation.

Compactin Absorption

Average oral absorption of pravastatin is 34% and absolute bioavailability is 17%.

Compactin side effects and Toxicity

Rhabdomyolysis; LD50=mg/kg (orally in rat)

Compactin Patient Information

Patients should be advised to report promptly unexplained muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever.

Compactin Organisms Affected

Humans and other mammals