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Physostigmine Brand names, Physostigmine Analogs

Physostigmine Brand Names Mixture

  • No information avaliable

Physostigmine Chemical_Formula


Physostigmine RX_link

Physostigmine fda sheet

Physostigmine msds (material safety sheet)

Physostigmine Synthesis Reference

Zhang J,et al. Appl Microbiol Biotechnol. 44(5):568-75.

Physostigmine Molecular Weight

275.346 g/mol

Physostigmine Melting Point

105.5 oC

Physostigmine H2O Solubility

7760 mg/L

Physostigmine State


Physostigmine LogP


Physostigmine Dosage Forms


Physostigmine Indication

For the treatment of glaucoma, and in the treatment of severe anticholinergic toxicity.

Physostigmine Pharmacology

Physostigmine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor which effectively increases the concentration of acetylcholine at the sites of cholinergic transmission. Physostigmine is used to treat glaucoma. Because it crosses the blood-brain barrier, it is also used to treat the central nervous system effects of atropine overdose and other anticholinergic drug overdoses. Physostigmine can reverse both central and peripheral anticholinergia.

Physostigmine Absorption

No information avaliable

Physostigmine side effects and Toxicity

Side effects include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth, blurred vision or change in near or distant vision, and eye pain.

Physostigmine Patient Information

No information avaliable

Physostigmine Organisms Affected

Humans and other mammals