PHYSOSTIGMINE 9599
Brand names,
PHYSOSTIGMINE 9599
Analogs
PHYSOSTIGMINE 9599
Brand Names Mixture
PHYSOSTIGMINE 9599
Chemical_Formula
C15H21N3O2
PHYSOSTIGMINE 9599
RX_link
http://www.rxlist.com/cgi/generic3/physostigmine.htm
PHYSOSTIGMINE 9599
fda sheet
PHYSOSTIGMINE 9599
msds (material safety sheet)
PHYSOSTIGMINE 9599
Synthesis Reference
Zhang J,et al. Appl Microbiol Biotechnol. 44(5):568-75.
PHYSOSTIGMINE 9599
Molecular Weight
275.346 g/mol
PHYSOSTIGMINE 9599
Melting Point
105.5 oC
PHYSOSTIGMINE 9599
H2O Solubility
7760 mg/L
PHYSOSTIGMINE 9599
State
Solid
PHYSOSTIGMINE 9599
LogP
1.582
PHYSOSTIGMINE 9599
Dosage Forms
Liquid
PHYSOSTIGMINE 9599
Indication
For the treatment of glaucoma, and in the treatment of severe anticholinergic toxicity.
PHYSOSTIGMINE 9599
Pharmacology
Physostigmine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor which effectively increases the concentration of acetylcholine at the sites of cholinergic transmission. Physostigmine is used to treat glaucoma. Because it crosses the blood-brain barrier, it is also used to treat the central nervous system effects of atropine overdose and other anticholinergic drug overdoses. Physostigmine can reverse both central and peripheral anticholinergia.
PHYSOSTIGMINE 9599
Absorption
No information avaliable
PHYSOSTIGMINE 9599
side effects and Toxicity
Side effects include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth, blurred vision or change in near or distant vision, and eye pain.
PHYSOSTIGMINE 9599
Patient Information
No information avaliable
PHYSOSTIGMINE 9599
Organisms Affected
Humans and other mammals