Esromiotin
Brand names,
Esromiotin
Analogs
Esromiotin
Brand Names Mixture
Esromiotin
Chemical_Formula
C15H21N3O2
Esromiotin
RX_link
http://www.rxlist.com/cgi/generic3/physostigmine.htm
Esromiotin
fda sheet
Esromiotin
msds (material safety sheet)
Esromiotin
Synthesis Reference
Zhang J,et al. Appl Microbiol Biotechnol. 44(5):568-75.
Esromiotin
Molecular Weight
275.346 g/mol
Esromiotin
Melting Point
105.5 oC
Esromiotin
H2O Solubility
7760 mg/L
Esromiotin
State
Solid
Esromiotin
LogP
1.582
Esromiotin
Dosage Forms
Liquid
Esromiotin
Indication
For the treatment of glaucoma, and in the treatment of severe anticholinergic toxicity.
Esromiotin
Pharmacology
Physostigmine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor which effectively increases the concentration of acetylcholine at the sites of cholinergic transmission. Physostigmine is used to treat glaucoma. Because it crosses the blood-brain barrier, it is also used to treat the central nervous system effects of atropine overdose and other anticholinergic drug overdoses. Physostigmine can reverse both central and peripheral anticholinergia.
Esromiotin
Absorption
No information avaliable
Esromiotin
side effects and Toxicity
Side effects include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth, blurred vision or change in near or distant vision, and eye pain.
Esromiotin
Patient Information
No information avaliable
Esromiotin
Organisms Affected
Humans and other mammals