Eserine Salicylate
Brand names,
Eserine Salicylate
Analogs
Eserine Salicylate
Brand Names Mixture
Eserine Salicylate
Chemical_Formula
C15H21N3O2
Eserine Salicylate
RX_link
http://www.rxlist.com/cgi/generic3/physostigmine.htm
Eserine Salicylate
fda sheet
Eserine Salicylate
msds (material safety sheet)
Eserine Salicylate
Synthesis Reference
Zhang J,et al. Appl Microbiol Biotechnol. 44(5):568-75.
Eserine Salicylate
Molecular Weight
275.346 g/mol
Eserine Salicylate
Melting Point
105.5 oC
Eserine Salicylate
H2O Solubility
7760 mg/L
Eserine Salicylate
State
Solid
Eserine Salicylate
LogP
1.582
Eserine Salicylate
Dosage Forms
Liquid
Eserine Salicylate
Indication
For the treatment of glaucoma, and in the treatment of severe anticholinergic toxicity.
Eserine Salicylate
Pharmacology
Physostigmine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor which effectively increases the concentration of acetylcholine at the sites of cholinergic transmission. Physostigmine is used to treat glaucoma. Because it crosses the blood-brain barrier, it is also used to treat the central nervous system effects of atropine overdose and other anticholinergic drug overdoses. Physostigmine can reverse both central and peripheral anticholinergia.
Eserine Salicylate
Absorption
No information avaliable
Eserine Salicylate
side effects and Toxicity
Side effects include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth, blurred vision or change in near or distant vision, and eye pain.
Eserine Salicylate
Patient Information
No information avaliable
Eserine Salicylate
Organisms Affected
Humans and other mammals