Ezerin

Ezerin Brand names, Ezerin Analogs

Ezerin Brand Names Mixture

No information avaliable

Ezerin Chemical_Formula

C₁₅H₂₁N₃O₂

Ezerin RX_link

http://www.rxlist.com/cgi/generic3/physostigmine.htm

Ezerin fda sheet

Ezerin msds (material safety sheet)

Ezerin Synthesis Reference

Zhang J,et al. Appl Microbiol Biotechnol. 44(5):568-75.

Ezerin Molecular Weight

275.346 g/mol

Ezerin Melting Point

105.5 ^oC

Ezerin H₂O Solubility

7760 mg/L

Ezerin State

Solid

Ezerin LogP

1.582

Ezerin Dosage Forms

Liquid

Ezerin Indication

For the treatment of glaucoma, and in the treatment of severe anticholinergic toxicity.

Ezerin Pharmacology

Physostigmine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor which effectively increases the concentration of acetylcholine at the sites of cholinergic transmission. Physostigmine is used to treat glaucoma. Because it crosses the blood-brain barrier, it is also used to treat the central nervous system effects of atropine overdose and other anticholinergic drug overdoses. Physostigmine can reverse both central and peripheral anticholinergia.

Ezerin Absorption

No information avaliable

Ezerin side effects and Toxicity

Side effects include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth, blurred vision or change in near or distant vision, and eye pain.

Ezerin Patient Information