Erserine
Brand names,
Erserine
Analogs
Erserine
Brand Names Mixture
Erserine
Chemical_Formula
C15H21N3O2
Erserine
RX_link
http://www.rxlist.com/cgi/generic3/physostigmine.htm
Erserine
fda sheet
Erserine
msds (material safety sheet)
Erserine
Synthesis Reference
Zhang J,et al. Appl Microbiol Biotechnol. 44(5):568-75.
Erserine
Molecular Weight
275.346 g/mol
Erserine
Melting Point
105.5 oC
Erserine
H2O Solubility
7760 mg/L
Erserine
State
Solid
Erserine
LogP
1.582
Erserine
Dosage Forms
Liquid
Erserine
Indication
For the treatment of glaucoma, and in the treatment of severe anticholinergic toxicity.
Erserine
Pharmacology
Physostigmine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor which effectively increases the concentration of acetylcholine at the sites of cholinergic transmission. Physostigmine is used to treat glaucoma. Because it crosses the blood-brain barrier, it is also used to treat the central nervous system effects of atropine overdose and other anticholinergic drug overdoses. Physostigmine can reverse both central and peripheral anticholinergia.
Erserine
Absorption
No information avaliable
Erserine
side effects and Toxicity
Side effects include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth, blurred vision or change in near or distant vision, and eye pain.
Erserine
Patient Information
No information avaliable
Erserine
Organisms Affected
Humans and other mammals