Eserine Sulfate
Brand names,
Eserine Sulfate
Analogs
Eserine Sulfate
Brand Names Mixture
Eserine Sulfate
Chemical_Formula
C15H21N3O2
Eserine Sulfate
RX_link
http://www.rxlist.com/cgi/generic3/physostigmine.htm
Eserine Sulfate
fda sheet
Eserine Sulfate
msds (material safety sheet)
Eserine Sulfate
Synthesis Reference
Zhang J,et al. Appl Microbiol Biotechnol. 44(5):568-75.
Eserine Sulfate
Molecular Weight
275.346 g/mol
Eserine Sulfate
Melting Point
105.5 oC
Eserine Sulfate
H2O Solubility
7760 mg/L
Eserine Sulfate
State
Solid
Eserine Sulfate
LogP
1.582
Eserine Sulfate
Dosage Forms
Liquid
Eserine Sulfate
Indication
For the treatment of glaucoma, and in the treatment of severe anticholinergic toxicity.
Eserine Sulfate
Pharmacology
Physostigmine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor which effectively increases the concentration of acetylcholine at the sites of cholinergic transmission. Physostigmine is used to treat glaucoma. Because it crosses the blood-brain barrier, it is also used to treat the central nervous system effects of atropine overdose and other anticholinergic drug overdoses. Physostigmine can reverse both central and peripheral anticholinergia.
Eserine Sulfate
Absorption
No information avaliable
Eserine Sulfate
side effects and Toxicity
Side effects include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth, blurred vision or change in near or distant vision, and eye pain.
Eserine Sulfate
Patient Information
No information avaliable
Eserine Sulfate
Organisms Affected
Humans and other mammals