Cogmine Eserine
Brand names,
Cogmine Eserine
Analogs
Cogmine Eserine
Brand Names Mixture
Cogmine Eserine
Chemical_Formula
C15H21N3O2
Cogmine Eserine
RX_link
http://www.rxlist.com/cgi/generic3/physostigmine.htm
Cogmine Eserine
fda sheet
Cogmine Eserine
msds (material safety sheet)
Cogmine Eserine
Synthesis Reference
Zhang J,et al. Appl Microbiol Biotechnol. 44(5):568-75.
Cogmine Eserine
Molecular Weight
275.346 g/mol
Cogmine Eserine
Melting Point
105.5 oC
Cogmine Eserine
H2O Solubility
7760 mg/L
Cogmine Eserine
State
Solid
Cogmine Eserine
LogP
1.582
Cogmine Eserine
Dosage Forms
Liquid
Cogmine Eserine
Indication
For the treatment of glaucoma, and in the treatment of severe anticholinergic toxicity.
Cogmine Eserine
Pharmacology
Physostigmine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor which effectively increases the concentration of acetylcholine at the sites of cholinergic transmission. Physostigmine is used to treat glaucoma. Because it crosses the blood-brain barrier, it is also used to treat the central nervous system effects of atropine overdose and other anticholinergic drug overdoses. Physostigmine can reverse both central and peripheral anticholinergia.
Cogmine Eserine
Absorption
No information avaliable
Cogmine Eserine
side effects and Toxicity
Side effects include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth, blurred vision or change in near or distant vision, and eye pain.
Cogmine Eserine
Patient Information
No information avaliable
Cogmine Eserine
Organisms Affected
Humans and other mammals