Eserine

Eserine Brand names, Eserine Analogs

Eserine Brand Names Mixture

No information avaliable

Eserine Chemical_Formula

C₁₅H₂₁N₃O₂

Eserine RX_link

http://www.rxlist.com/cgi/generic3/physostigmine.htm

Eserine fda sheet

Eserine msds (material safety sheet)

Eserine Synthesis Reference

Zhang J,et al. Appl Microbiol Biotechnol. 44(5):568-75.

Eserine Molecular Weight

275.346 g/mol

Eserine Melting Point

105.5 ^oC

Eserine H₂O Solubility

7760 mg/L

Eserine State

Solid

Eserine LogP

1.582

Eserine Dosage Forms

Liquid

Eserine Indication

For the treatment of glaucoma, and in the treatment of severe anticholinergic toxicity.

Eserine Pharmacology

Physostigmine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor which effectively increases the concentration of acetylcholine at the sites of cholinergic transmission. Physostigmine is used to treat glaucoma. Because it crosses the blood-brain barrier, it is also used to treat the central nervous system effects of atropine overdose and other anticholinergic drug overdoses. Physostigmine can reverse both central and peripheral anticholinergia.

Eserine Absorption

No information avaliable

Eserine side effects and Toxicity

Side effects include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth, blurred vision or change in near or distant vision, and eye pain.

Eserine Patient Information