Eserolein, Methylcarbamate
Brand names,
Eserolein, Methylcarbamate
Analogs
Eserolein, Methylcarbamate
Brand Names Mixture
Eserolein, Methylcarbamate
Chemical_Formula
C15H21N3O2
Eserolein, Methylcarbamate
RX_link
http://www.rxlist.com/cgi/generic3/physostigmine.htm
Eserolein, Methylcarbamate
fda sheet
Eserolein, Methylcarbamate
msds (material safety sheet)
Eserolein, Methylcarbamate
Synthesis Reference
Zhang J,et al. Appl Microbiol Biotechnol. 44(5):568-75.
Eserolein, Methylcarbamate
Molecular Weight
275.346 g/mol
Eserolein, Methylcarbamate
Melting Point
105.5 oC
Eserolein, Methylcarbamate
H2O Solubility
7760 mg/L
Eserolein, Methylcarbamate
State
Solid
Eserolein, Methylcarbamate
LogP
1.582
Eserolein, Methylcarbamate
Dosage Forms
Liquid
Eserolein, Methylcarbamate
Indication
For the treatment of glaucoma, and in the treatment of severe anticholinergic toxicity.
Eserolein, Methylcarbamate
Pharmacology
Physostigmine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor which effectively increases the concentration of acetylcholine at the sites of cholinergic transmission. Physostigmine is used to treat glaucoma. Because it crosses the blood-brain barrier, it is also used to treat the central nervous system effects of atropine overdose and other anticholinergic drug overdoses. Physostigmine can reverse both central and peripheral anticholinergia.
Eserolein, Methylcarbamate
Absorption
No information avaliable
Eserolein, Methylcarbamate
side effects and Toxicity
Side effects include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth, blurred vision or change in near or distant vision, and eye pain.
Eserolein, Methylcarbamate
Patient Information
No information avaliable
Eserolein, Methylcarbamate
Organisms Affected
Humans and other mammals