Fysostigmin

Fysostigmin Brand names, Fysostigmin Analogs

Fysostigmin Brand Names Mixture

No information avaliable

Fysostigmin Chemical_Formula

C₁₅H₂₁N₃O₂

Fysostigmin RX_link

http://www.rxlist.com/cgi/generic3/physostigmine.htm

Fysostigmin fda sheet

Fysostigmin msds (material safety sheet)

Fysostigmin Synthesis Reference

Zhang J,et al. Appl Microbiol Biotechnol. 44(5):568-75.

Fysostigmin Molecular Weight

275.346 g/mol

Fysostigmin Melting Point

105.5 ^oC

Fysostigmin H₂O Solubility

7760 mg/L

Fysostigmin State

Solid

Fysostigmin LogP

1.582

Fysostigmin Dosage Forms

Liquid

Fysostigmin Indication

For the treatment of glaucoma, and in the treatment of severe anticholinergic toxicity.

Fysostigmin Pharmacology

Physostigmine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor which effectively increases the concentration of acetylcholine at the sites of cholinergic transmission. Physostigmine is used to treat glaucoma. Because it crosses the blood-brain barrier, it is also used to treat the central nervous system effects of atropine overdose and other anticholinergic drug overdoses. Physostigmine can reverse both central and peripheral anticholinergia.

Fysostigmin Absorption

No information avaliable

Fysostigmin side effects and Toxicity

Side effects include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth, blurred vision or change in near or distant vision, and eye pain.

Fysostigmin Patient Information