Norflex en es it fr

Norflex Brand names, Norflex Analogs

Norflex Brand Names Mixture

  • No information avaliable

Norflex Chemical_Formula


Norflex RX_link

Norflex fda sheet

Norflex FDA

Norflex msds (material safety sheet)

Norflex MSDS

Norflex Synthesis Reference

No information avaliable

Norflex Molecular Weight

269.381 g/mol

Norflex Melting Point

156-157 oC

Norflex H2O Solubility

Sparingly soluble in water

Norflex State


Norflex LogP


Norflex Dosage Forms

Tablet (extended-release)

Norflex Indication

Indicated for the treatment of Parkinson's disease.

Norflex Pharmacology

Orphenadrine is indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute painful musculoskeletal conditions. Orphenadrine is an anticholinergic with a predominantly central effect and only a weak peripheral effect. In addition, it has mild antihistaminic and local anaesthetic properties. Parkinson's syndrome is the consequence of a disturbed balance between cholinergic and dopaminergic neurotransmission in the basal ganglia caused by a decrease in dopamine. Orphenadrine restores the physiological equilibrium and has a favourable effect on the rigidity and tremor of Parkinson's disease and Parkinsonian syndromes. The effect is somewhat less on bradykinesia.

Norflex Absorption

Orphenadrine is almost completely absorbed in the gastrointestinal tract.

Norflex side effects and Toxicity

Oral, mouse LD50 = 100 mg/kg; oral, rat LD50 = 255 mg/kg

Norflex Patient Information

No information avaliable

Norflex Organisms Affected

Humans and other mammals