Banflex

Banflex Brand names, Banflex Analogs

Banflex Brand Names Mixture

No information avaliable

Banflex Chemical_Formula

C₁₈H₂₃NO

Banflex RX_link

http://www.rxlist.com/cgi/generic/orphen.htm

Banflex fda sheet

Banflex FDA

Banflex msds (material safety sheet)

Banflex MSDS

Banflex Synthesis Reference

No information avaliable

Banflex Molecular Weight

269.381 g/mol

Banflex Melting Point

156-157 ^oC

Banflex H₂O Solubility

Sparingly soluble in water

Banflex State

Solid

Banflex LogP

4.034

Banflex Dosage Forms

Tablet (extended-release)

Banflex Indication

Indicated for the treatment of Parkinson's disease.

Banflex Pharmacology

Orphenadrine is indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute painful musculoskeletal conditions. Orphenadrine is an anticholinergic with a predominantly central effect and only a weak peripheral effect. In addition, it has mild antihistaminic and local anaesthetic properties. Parkinson's syndrome is the consequence of a disturbed balance between cholinergic and dopaminergic neurotransmission in the basal ganglia caused by a decrease in dopamine. Orphenadrine restores the physiological equilibrium and has a favourable effect on the rigidity and tremor of Parkinson's disease and Parkinsonian syndromes. The effect is somewhat less on bradykinesia.

Banflex Absorption

Orphenadrine is almost completely absorbed in the gastrointestinal tract.

Banflex side effects and Toxicity

Oral, mouse LD₅₀ = 100 mg/kg; oral, rat LD₅₀ = 255 mg/kg

Banflex Patient Information