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Gammacorten Brand names, Gammacorten Analogs

Gammacorten Brand Names Mixture

  • Ak Trol Suspension (Dexamethasone + Neomycin Sulfate + Polymyxin B Sulfate)
  • Ciprodex (Ciprofloxacin (Ciprofloxacin Hydrochloride) + Dexamethasone)
  • Cresophene Liq (Camphor + Chlorophenol + Dexamethasone + Thymol)
  • Dioptrol Ointment (Dexamethasone + Neomycin Sulfate + Polymyxin B Sulfate)
  • Dioptrol Suspension (Dexamethasone + Neomycin (Neomycin Sulfate) + Polymyxin B Sulfate)
  • Endomethasone Ivory (Dexamethasone + Hydrocortisone Acetate + Paraformaldehyde + Thymol Iodide)
  • Maxitrol (Dexamethasone + Neomycin (Neomycin Sulfate) + Polymyxin B Sulfate)
  • Maxitrol Ont (Dexamethasone + Neomycin (Neomycin Sulfate) + Polymyxin B Sulfate)
  • Naquasone Bolus (Dexamethasone + Trichlormethiazide)
  • Naquasone Inj (Dexamethasone + Trichlormethiazide)
  • Neodecadron Eye Ear Soln 0.1% (Dexamethasone Phosphate (Dexamethasone Sodium Phosphate) + Neomycin Sulfate)
  • Pendamine (Chlorpheniramine Maleate + Dexamethasone + Dihydrostreptomycin Sulfate + Penicillin G Procaine)
  • Sandoz Opticort (Dexamethasone (Dexamethasone Sodium Metasulphobenzoate) + Framycetin Sulfate + Gramicidin)
  • Septomixine Forte (Dexamethasone + Halethazole Tartrate + Neomycin (Neomycin Sulfate) + Polymyxin B Sulfate + Tyrothricin)
  • Sofracort Ear/Eye Ointment (Dexamethasone + Framycetin Sulfate + Gramicidin)
  • Sofracort Eye/Ear Drops (Dexamethasone Sodium Metasulphobenzoate + Framycetin Sulfate + Gramicidin)
  • Sofracort Sterile Ear/Eye Drops (Dexamethasone (Dexamethasone Sodium Metasulphobenzoate) + Framycetin Sulfate + Gramicidin)
  • Sofracort Sterile Ear/Eye Ointment (Dexamethasone + Framycetin Sulfate + Gramicidin)
  • Tobradex Oph Ointment (Dexamethasone + Tobramycin)
  • Tobradex Oph Sus (Dexamethasone + Tobramycin)
  • Tresaderm Dermatologic Solution (Dexamethasone + Neomycin (Neomycin Sulfate) + Thiabendazole)

Gammacorten Chemical_Formula

C22H29FO5

Gammacorten RX_link

http://www.rxlist.com/cgi/generic/dexameth.htm

Gammacorten fda sheet

Gammacorten FDA

Gammacorten msds (material safety sheet)

Gammacorten MSDS

Gammacorten Synthesis Reference

Chemerda et al.; U.S. Pat. 2,939,873 (1960)

Gammacorten Molecular Weight

392.461 g/mol

Gammacorten Melting Point

262 oC

Gammacorten H2O Solubility

89 mg/L

Gammacorten State

Solid

Gammacorten LogP

1.772

Gammacorten Dosage Forms

Drops; Elixir; Implant; Liquid; Ointment; Powder; Solution; Tablet

Gammacorten Indication

Injection: for the treatment of endocrine disorders, rheumatic D=disorders, collagen diseases, dermatologic diseases, allergic statesc, ophthalmic diseases, gastrointestinal diseases, respiratory diseases, hematologic disorders, neoplastic diseases, edematous states, cerebral edema.

Gammacorten Pharmacology

Dexamethasone and its derivatives, dexamethasone sodium phosphate and dexamethasone acetate, are synthetic glucocorticoids. Used for its antiinflammatory or immunosuppressive properties and ability to penetrate the CNS, dexamethasone is used alone to manage cerebral edema and with tobramycin to treat corticosteroid-responsive inflammatory ocular conditions.

Gammacorten Absorption

80-90%

Gammacorten side effects and Toxicity

Oral, rat LD50: >3 gm/kg. Signs of overdose include retinal toxicity, glaucoma, subcapsular cataract, gastrointestinal bleeding, pancreatitis, aseptic bone necrosis, osteoporosis, myopathies, obesity, edemas, hypertension, proteinuria, diabetes, sleep disturbances, psychiatric syndromes, delayed wound healing, atrophy and fragility of the skin, ecchymosis, and pseudotumor cerebri.

Gammacorten Patient Information

Gammacorten Organisms Affected

Humans and other mammals