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Cortisumman Brand names, Cortisumman Analogs

Cortisumman Brand Names Mixture

  • Ak Trol Suspension (Dexamethasone + Neomycin Sulfate + Polymyxin B Sulfate)
  • Ciprodex (Ciprofloxacin (Ciprofloxacin Hydrochloride) + Dexamethasone)
  • Cresophene Liq (Camphor + Chlorophenol + Dexamethasone + Thymol)
  • Dioptrol Ointment (Dexamethasone + Neomycin Sulfate + Polymyxin B Sulfate)
  • Dioptrol Suspension (Dexamethasone + Neomycin (Neomycin Sulfate) + Polymyxin B Sulfate)
  • Endomethasone Ivory (Dexamethasone + Hydrocortisone Acetate + Paraformaldehyde + Thymol Iodide)
  • Maxitrol (Dexamethasone + Neomycin (Neomycin Sulfate) + Polymyxin B Sulfate)
  • Maxitrol Ont (Dexamethasone + Neomycin (Neomycin Sulfate) + Polymyxin B Sulfate)
  • Naquasone Bolus (Dexamethasone + Trichlormethiazide)
  • Naquasone Inj (Dexamethasone + Trichlormethiazide)
  • Neodecadron Eye Ear Soln 0.1% (Dexamethasone Phosphate (Dexamethasone Sodium Phosphate) + Neomycin Sulfate)
  • Pendamine (Chlorpheniramine Maleate + Dexamethasone + Dihydrostreptomycin Sulfate + Penicillin G Procaine)
  • Sandoz Opticort (Dexamethasone (Dexamethasone Sodium Metasulphobenzoate) + Framycetin Sulfate + Gramicidin)
  • Septomixine Forte (Dexamethasone + Halethazole Tartrate + Neomycin (Neomycin Sulfate) + Polymyxin B Sulfate + Tyrothricin)
  • Sofracort Ear/Eye Ointment (Dexamethasone + Framycetin Sulfate + Gramicidin)
  • Sofracort Eye/Ear Drops (Dexamethasone Sodium Metasulphobenzoate + Framycetin Sulfate + Gramicidin)
  • Sofracort Sterile Ear/Eye Drops (Dexamethasone (Dexamethasone Sodium Metasulphobenzoate) + Framycetin Sulfate + Gramicidin)
  • Sofracort Sterile Ear/Eye Ointment (Dexamethasone + Framycetin Sulfate + Gramicidin)
  • Tobradex Oph Ointment (Dexamethasone + Tobramycin)
  • Tobradex Oph Sus (Dexamethasone + Tobramycin)
  • Tresaderm Dermatologic Solution (Dexamethasone + Neomycin (Neomycin Sulfate) + Thiabendazole)

Cortisumman Chemical_Formula

C22H29FO5

Cortisumman RX_link

http://www.rxlist.com/cgi/generic/dexameth.htm

Cortisumman fda sheet

Cortisumman FDA

Cortisumman msds (material safety sheet)

Cortisumman MSDS

Cortisumman Synthesis Reference

Chemerda et al.; U.S. Pat. 2,939,873 (1960)

Cortisumman Molecular Weight

392.461 g/mol

Cortisumman Melting Point

262 oC

Cortisumman H2O Solubility

89 mg/L

Cortisumman State

Solid

Cortisumman LogP

1.772

Cortisumman Dosage Forms

Drops; Elixir; Implant; Liquid; Ointment; Powder; Solution; Tablet

Cortisumman Indication

Injection: for the treatment of endocrine disorders, rheumatic D=disorders, collagen diseases, dermatologic diseases, allergic statesc, ophthalmic diseases, gastrointestinal diseases, respiratory diseases, hematologic disorders, neoplastic diseases, edematous states, cerebral edema.

Cortisumman Pharmacology

Dexamethasone and its derivatives, dexamethasone sodium phosphate and dexamethasone acetate, are synthetic glucocorticoids. Used for its antiinflammatory or immunosuppressive properties and ability to penetrate the CNS, dexamethasone is used alone to manage cerebral edema and with tobramycin to treat corticosteroid-responsive inflammatory ocular conditions.

Cortisumman Absorption

80-90%

Cortisumman side effects and Toxicity

Oral, rat LD50: >3 gm/kg. Signs of overdose include retinal toxicity, glaucoma, subcapsular cataract, gastrointestinal bleeding, pancreatitis, aseptic bone necrosis, osteoporosis, myopathies, obesity, edemas, hypertension, proteinuria, diabetes, sleep disturbances, psychiatric syndromes, delayed wound healing, atrophy and fragility of the skin, ecchymosis, and pseudotumor cerebri.

Cortisumman Patient Information

Cortisumman Organisms Affected

Humans and other mammals