Corsone

Corsone Brand names, Corsone Analogs

Corsone Brand Names Mixture

Ak Trol Suspension (Dexamethasone + Neomycin Sulfate + Polymyxin B Sulfate)
Ciprodex (Ciprofloxacin (Ciprofloxacin Hydrochloride) + Dexamethasone)
Cresophene Liq (Camphor + Chlorophenol + Dexamethasone + Thymol)
Dioptrol Ointment (Dexamethasone + Neomycin Sulfate + Polymyxin B Sulfate)
Dioptrol Suspension (Dexamethasone + Neomycin (Neomycin Sulfate) + Polymyxin B Sulfate)
Endomethasone Ivory (Dexamethasone + Hydrocortisone Acetate + Paraformaldehyde + Thymol Iodide)
Maxitrol (Dexamethasone + Neomycin (Neomycin Sulfate) + Polymyxin B Sulfate)
Maxitrol Ont (Dexamethasone + Neomycin (Neomycin Sulfate) + Polymyxin B Sulfate)
Naquasone Bolus (Dexamethasone + Trichlormethiazide)
Naquasone Inj (Dexamethasone + Trichlormethiazide)
Neodecadron Eye Ear Soln 0.1% (Dexamethasone Phosphate (Dexamethasone Sodium Phosphate) + Neomycin Sulfate)
Pendamine (Chlorpheniramine Maleate + Dexamethasone + Dihydrostreptomycin Sulfate + Penicillin G Procaine)
Sandoz Opticort (Dexamethasone (Dexamethasone Sodium Metasulphobenzoate) + Framycetin Sulfate + Gramicidin)
Septomixine Forte (Dexamethasone + Halethazole Tartrate + Neomycin (Neomycin Sulfate) + Polymyxin B Sulfate + Tyrothricin)
Sofracort Ear/Eye Ointment (Dexamethasone + Framycetin Sulfate + Gramicidin)
Sofracort Eye/Ear Drops (Dexamethasone Sodium Metasulphobenzoate + Framycetin Sulfate + Gramicidin)
Sofracort Sterile Ear/Eye Drops (Dexamethasone (Dexamethasone Sodium Metasulphobenzoate) + Framycetin Sulfate + Gramicidin)
Sofracort Sterile Ear/Eye Ointment (Dexamethasone + Framycetin Sulfate + Gramicidin)
Tobradex Oph Ointment (Dexamethasone + Tobramycin)
Tobradex Oph Sus (Dexamethasone + Tobramycin)
Tresaderm Dermatologic Solution (Dexamethasone + Neomycin (Neomycin Sulfate) + Thiabendazole)

Corsone Chemical_Formula

C₂₂H₂₉FO₅

Corsone RX_link

http://www.rxlist.com/cgi/generic/dexameth.htm

Corsone fda sheet

Corsone FDA

Corsone msds (material safety sheet)

Corsone MSDS

Corsone Synthesis Reference

Chemerda et al.; U.S. Pat. 2,939,873 (1960)

Corsone Molecular Weight

392.461 g/mol

Corsone Melting Point

262 ^oC

Corsone H₂O Solubility

89 mg/L

Corsone State

Solid

Corsone LogP

1.772

Corsone Dosage Forms

Drops; Elixir; Implant; Liquid; Ointment; Powder; Solution; Tablet

Corsone Indication

Injection: for the treatment of endocrine disorders, rheumatic D=disorders, collagen diseases, dermatologic diseases, allergic statesc, ophthalmic diseases, gastrointestinal diseases, respiratory diseases, hematologic disorders, neoplastic diseases, edematous states, cerebral edema.

Corsone Pharmacology

Dexamethasone and its derivatives, dexamethasone sodium phosphate and dexamethasone acetate, are synthetic glucocorticoids. Used for its antiinflammatory or immunosuppressive properties and ability to penetrate the CNS, dexamethasone is used alone to manage cerebral edema and with tobramycin to treat corticosteroid-responsive inflammatory ocular conditions.

Corsone Absorption

80-90%

Corsone side effects and Toxicity

Oral, rat LD₅₀: >3 gm/kg. Signs of overdose include retinal toxicity, glaucoma, subcapsular cataract, gastrointestinal bleeding, pancreatitis, aseptic bone necrosis, osteoporosis, myopathies, obesity, edemas, hypertension, proteinuria, diabetes, sleep disturbances, psychiatric syndromes, delayed wound healing, atrophy and fragility of the skin, ecchymosis, and pseudotumor cerebri.

Corsone Patient Information

Corsone Organisms Affected

Humans and other mammals