Desamethasone

Desamethasone Brand names, Desamethasone Analogs

Desamethasone Brand Names Mixture

Ak Trol Suspension (Dexamethasone + Neomycin Sulfate + Polymyxin B Sulfate)
Ciprodex (Ciprofloxacin (Ciprofloxacin Hydrochloride) + Dexamethasone)
Cresophene Liq (Camphor + Chlorophenol + Dexamethasone + Thymol)
Dioptrol Ointment (Dexamethasone + Neomycin Sulfate + Polymyxin B Sulfate)
Dioptrol Suspension (Dexamethasone + Neomycin (Neomycin Sulfate) + Polymyxin B Sulfate)
Endomethasone Ivory (Dexamethasone + Hydrocortisone Acetate + Paraformaldehyde + Thymol Iodide)
Maxitrol (Dexamethasone + Neomycin (Neomycin Sulfate) + Polymyxin B Sulfate)
Maxitrol Ont (Dexamethasone + Neomycin (Neomycin Sulfate) + Polymyxin B Sulfate)
Naquasone Bolus (Dexamethasone + Trichlormethiazide)
Naquasone Inj (Dexamethasone + Trichlormethiazide)
Neodecadron Eye Ear Soln 0.1% (Dexamethasone Phosphate (Dexamethasone Sodium Phosphate) + Neomycin Sulfate)
Pendamine (Chlorpheniramine Maleate + Dexamethasone + Dihydrostreptomycin Sulfate + Penicillin G Procaine)
Sandoz Opticort (Dexamethasone (Dexamethasone Sodium Metasulphobenzoate) + Framycetin Sulfate + Gramicidin)
Septomixine Forte (Dexamethasone + Halethazole Tartrate + Neomycin (Neomycin Sulfate) + Polymyxin B Sulfate + Tyrothricin)
Sofracort Ear/Eye Ointment (Dexamethasone + Framycetin Sulfate + Gramicidin)
Sofracort Eye/Ear Drops (Dexamethasone Sodium Metasulphobenzoate + Framycetin Sulfate + Gramicidin)
Sofracort Sterile Ear/Eye Drops (Dexamethasone (Dexamethasone Sodium Metasulphobenzoate) + Framycetin Sulfate + Gramicidin)
Sofracort Sterile Ear/Eye Ointment (Dexamethasone + Framycetin Sulfate + Gramicidin)
Tobradex Oph Ointment (Dexamethasone + Tobramycin)
Tobradex Oph Sus (Dexamethasone + Tobramycin)
Tresaderm Dermatologic Solution (Dexamethasone + Neomycin (Neomycin Sulfate) + Thiabendazole)

Desamethasone Chemical_Formula

C₂₂H₂₉FO₅

Desamethasone RX_link

http://www.rxlist.com/cgi/generic/dexameth.htm

Desamethasone fda sheet

Desamethasone FDA

Desamethasone msds (material safety sheet)

Desamethasone MSDS

Desamethasone Synthesis Reference

Chemerda et al.; U.S. Pat. 2,939,873 (1960)

Desamethasone Molecular Weight

392.461 g/mol

Desamethasone Melting Point

262 ^oC

Desamethasone H₂O Solubility

89 mg/L

Desamethasone State

Solid

Desamethasone LogP

1.772

Desamethasone Dosage Forms

Drops; Elixir; Implant; Liquid; Ointment; Powder; Solution; Tablet

Desamethasone Indication

Injection: for the treatment of endocrine disorders, rheumatic D=disorders, collagen diseases, dermatologic diseases, allergic statesc, ophthalmic diseases, gastrointestinal diseases, respiratory diseases, hematologic disorders, neoplastic diseases, edematous states, cerebral edema.

Desamethasone Pharmacology

Dexamethasone and its derivatives, dexamethasone sodium phosphate and dexamethasone acetate, are synthetic glucocorticoids. Used for its antiinflammatory or immunosuppressive properties and ability to penetrate the CNS, dexamethasone is used alone to manage cerebral edema and with tobramycin to treat corticosteroid-responsive inflammatory ocular conditions.

Desamethasone Absorption

80-90%

Desamethasone side effects and Toxicity

Oral, rat LD₅₀: >3 gm/kg. Signs of overdose include retinal toxicity, glaucoma, subcapsular cataract, gastrointestinal bleeding, pancreatitis, aseptic bone necrosis, osteoporosis, myopathies, obesity, edemas, hypertension, proteinuria, diabetes, sleep disturbances, psychiatric syndromes, delayed wound healing, atrophy and fragility of the skin, ecchymosis, and pseudotumor cerebri.

Desamethasone Patient Information

Desamethasone Organisms Affected

Humans and other mammals