Aphthasolone
Aphthasolone Brand names, Aphthasolone Analogs
- Adexone
- Aeroseb-D
- Aeroseb-Dex
- Anaflogistico
- Aphtasolon
- Aphthasolone
- Auxiron
- Azium
- Bisu Ds
- Calonat
- Corson
- Corsone
- Cortisumman
- DEX
- DXM
- Decacort
- Decacortin
- Decaderm
- Decadron
- Decadron Tablets, Elixir
- Decadron-La
- Decagel
- Decalix
- Decasone
- Decaspray
- Dectancyl
- Dekacort
- Deltafluorene
- Dergramin
- Deronil
- Desadrene
- Desametasone
- Desametasone [Dcit]
- Desamethasone
- Desameton
- Deseronil
- Dex-Ide
- Dexa
- Dexa Mamallet
- Dexa-Cortidelt
- Dexa-Cortisyl
- Dexa-Mamallet
- Dexa-Scheroson
- Dexa-Sine
- Dexacen-4
- Dexacidin
- Dexacort
- Dexacortal
- Dexacortin
- Dexadeltone
- Dexafarma
- Dexair
- Dexalona
- Dexaltin
- Dexametasona [Inn-Spanish]
- Dexameth
- Dexamethasone Acetate
- Dexamethasone Alcohol
- Dexamethasone Base
- Dexamethasone Intensol
- Dexamethasone Sodium Phosphate
- Dexamethasone [Ban:Inn:Jan]
- Dexamethasonum [Inn-Latin]
- Dexamethazone
- Dexamonozon
- Dexapolcort
- Dexapos
- Dexaprol
- Dexason
- Dexasone
- Dexinolon
- Dexinoral
- Dexone
- Dexone 0.5
- Dexone 0.75
- Dexone 1.5
- Dexone 4
- Dexonium
- Dextelan
- Dezone
- Dinormon
- Dxms
- Fluormethylprednisolone
- Fluormone
- Fluorocort
- Fortecortin
- Gammacorten
- Hexadecadrol
- Hexadrol
- Hexadrol Elixir
- Hexadrol Tablets
- Hl-Dex
- Isopto-Dex
- Lokalison F
- Loverine
- Luxazone
- Maxidex
- Maxitrol
- Mediamethasone
- Mexidex
- Millicorten
- Mymethasone
- Ocu-Trol
- Oradexon
- Pet Derm Iii
- Pet-Derm Iii
- Policort
- Prednisolon F
- Prednisolone F
- Sk-Dexamethasone
- Spoloven
- Sunia Sol D
- Superprednol
- Tobradex
- Turbinaire
- Visumetazone
Aphthasolone Brand Names Mixture
- Ak Trol Suspension (Dexamethasone + Neomycin Sulfate + Polymyxin B Sulfate)
- Ciprodex (Ciprofloxacin (Ciprofloxacin Hydrochloride) + Dexamethasone)
- Cresophene Liq (Camphor + Chlorophenol + Dexamethasone + Thymol)
- Dioptrol Ointment (Dexamethasone + Neomycin Sulfate + Polymyxin B Sulfate)
- Dioptrol Suspension (Dexamethasone + Neomycin (Neomycin Sulfate) + Polymyxin B Sulfate)
- Endomethasone Ivory (Dexamethasone + Hydrocortisone Acetate + Paraformaldehyde + Thymol Iodide)
- Maxitrol (Dexamethasone + Neomycin (Neomycin Sulfate) + Polymyxin B Sulfate)
- Maxitrol Ont (Dexamethasone + Neomycin (Neomycin Sulfate) + Polymyxin B Sulfate)
- Naquasone Bolus (Dexamethasone + Trichlormethiazide)
- Naquasone Inj (Dexamethasone + Trichlormethiazide)
- Neodecadron Eye Ear Soln 0.1% (Dexamethasone Phosphate (Dexamethasone Sodium Phosphate) + Neomycin Sulfate)
- Pendamine (Chlorpheniramine Maleate + Dexamethasone + Dihydrostreptomycin Sulfate + Penicillin G Procaine)
- Sandoz Opticort (Dexamethasone (Dexamethasone Sodium Metasulphobenzoate) + Framycetin Sulfate + Gramicidin)
- Septomixine Forte (Dexamethasone + Halethazole Tartrate + Neomycin (Neomycin Sulfate) + Polymyxin B Sulfate + Tyrothricin)
- Sofracort Ear/Eye Ointment (Dexamethasone + Framycetin Sulfate + Gramicidin)
- Sofracort Eye/Ear Drops (Dexamethasone Sodium Metasulphobenzoate + Framycetin Sulfate + Gramicidin)
- Sofracort Sterile Ear/Eye Drops (Dexamethasone (Dexamethasone Sodium Metasulphobenzoate) + Framycetin Sulfate + Gramicidin)
- Sofracort Sterile Ear/Eye Ointment (Dexamethasone + Framycetin Sulfate + Gramicidin)
- Tobradex Oph Ointment (Dexamethasone + Tobramycin)
- Tobradex Oph Sus (Dexamethasone + Tobramycin)
- Tresaderm Dermatologic Solution (Dexamethasone + Neomycin (Neomycin Sulfate) + Thiabendazole)
Aphthasolone Chemical_Formula
C22H29FO5
Aphthasolone RX_link
http://www.rxlist.com/cgi/generic/dexameth.htm
Aphthasolone fda sheet
Aphthasolone msds (material safety sheet)
Aphthasolone Synthesis Reference
Chemerda et al.; U.S. Pat. 2,939,873 (1960)
Aphthasolone Molecular Weight
392.461 g/mol
Aphthasolone Melting Point
262 oC
Aphthasolone H2O Solubility
89 mg/L
Aphthasolone State
Solid
Aphthasolone LogP
1.772
Aphthasolone Dosage Forms
Drops; Elixir; Implant; Liquid; Ointment; Powder; Solution; Tablet
Aphthasolone Indication
Injection: for the treatment of endocrine disorders, rheumatic D=disorders, collagen diseases, dermatologic diseases, allergic statesc, ophthalmic diseases, gastrointestinal diseases, respiratory diseases, hematologic disorders, neoplastic diseases, edematous states, cerebral edema.
Aphthasolone Pharmacology
Dexamethasone and its derivatives, dexamethasone sodium phosphate and dexamethasone acetate, are synthetic glucocorticoids. Used for its antiinflammatory or immunosuppressive properties and ability to penetrate the CNS, dexamethasone is used alone to manage cerebral edema and with tobramycin to treat corticosteroid-responsive inflammatory ocular conditions.
Aphthasolone Absorption
80-90%
Aphthasolone side effects and Toxicity
Oral, rat LD50: >3 gm/kg. Signs of overdose include retinal toxicity, glaucoma, subcapsular cataract, gastrointestinal bleeding, pancreatitis, aseptic bone necrosis, osteoporosis, myopathies, obesity, edemas, hypertension, proteinuria, diabetes, sleep disturbances, psychiatric syndromes, delayed wound healing, atrophy and fragility of the skin, ecchymosis, and pseudotumor cerebri.
Aphthasolone Patient Information
Aphthasolone Organisms Affected
Humans and other mammals
