PharmacyCodes



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CAF Brand names, CAF Analogs

CAF Brand Names Mixture

  • No information avaliable

CAF Chemical_Formula

C11H15NO

CAF RX_link

No information avaliable

CAF fda sheet

CAF msds (material safety sheet)

CAF MSDS

CAF Synthesis Reference

No information avaliable

CAF Molecular Weight

177.243 g/mol

CAF Melting Point

139 oC

CAF H2O Solubility

>5 mg/L

CAF State

Solid

CAF LogP

1.796

CAF Dosage Forms

Tablet

CAF Indication

Used as an anorectic in the treatment of obesity.

CAF Pharmacology

Phenmetrazine is a sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine. Amphetamines are non-catecholamine sympathomimetic amines with CNS stimulant activity. Phenmetrazine was originally sold under the tradename Preludin as an anorectic. It has since been removed from the market. It is by some considered to have a greater potential for addiction than the amphetamines, and has been abused in many countries, for example Sweden.

CAF Absorption

Readily absorbed from the gastro-intestinal tract and buccal mucosa.

CAF side effects and Toxicity

Adult monkeys have an LD50 of 15 to 20 mg/kg, whereas for young monkeys the LD50 is only 5 mg/kg. Symptoms of overdose include acute central nervous system stimulation, cardiotoxicity causing tachycardia, arrhythmias, hypertension, and cardiovascular collapse. Whilst some patients show signs of toxicity at blood concentrations of 20 µg/L, chronic abusers of amphetamine have been known to have blood concentration of up to 3000 µg/L.

CAF Patient Information

No information avaliable

CAF Organisms Affected

Humans and other mammals