PharmacyCodes



Dexphenmetrazine en es it fr

Dexphenmetrazine Brand names, Dexphenmetrazine Analogs

Dexphenmetrazine Brand Names Mixture

  • No information avaliable

Dexphenmetrazine Chemical_Formula

C11H15NO

Dexphenmetrazine RX_link

No information avaliable

Dexphenmetrazine fda sheet

Dexphenmetrazine msds (material safety sheet)

Dexphenmetrazine MSDS

Dexphenmetrazine Synthesis Reference

No information avaliable

Dexphenmetrazine Molecular Weight

177.243 g/mol

Dexphenmetrazine Melting Point

139 oC

Dexphenmetrazine H2O Solubility

>5 mg/L

Dexphenmetrazine State

Solid

Dexphenmetrazine LogP

1.796

Dexphenmetrazine Dosage Forms

Tablet

Dexphenmetrazine Indication

Used as an anorectic in the treatment of obesity.

Dexphenmetrazine Pharmacology

Phenmetrazine is a sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine. Amphetamines are non-catecholamine sympathomimetic amines with CNS stimulant activity. Phenmetrazine was originally sold under the tradename Preludin as an anorectic. It has since been removed from the market. It is by some considered to have a greater potential for addiction than the amphetamines, and has been abused in many countries, for example Sweden.

Dexphenmetrazine Absorption

Readily absorbed from the gastro-intestinal tract and buccal mucosa.

Dexphenmetrazine side effects and Toxicity

Adult monkeys have an LD50 of 15 to 20 mg/kg, whereas for young monkeys the LD50 is only 5 mg/kg. Symptoms of overdose include acute central nervous system stimulation, cardiotoxicity causing tachycardia, arrhythmias, hypertension, and cardiovascular collapse. Whilst some patients show signs of toxicity at blood concentrations of 20 µg/L, chronic abusers of amphetamine have been known to have blood concentration of up to 3000 µg/L.

Dexphenmetrazine Patient Information

No information avaliable

Dexphenmetrazine Organisms Affected

Humans and other mammals