Phenmetrazinum [INN-Latin] en es it fr

Phenmetrazinum [INN-Latin] Brand names, Phenmetrazinum [INN-Latin] Analogs

Phenmetrazinum [INN-Latin] Brand Names Mixture

  • No information avaliable

Phenmetrazinum [INN-Latin] Chemical_Formula


Phenmetrazinum [INN-Latin] RX_link

No information avaliable

Phenmetrazinum [INN-Latin] fda sheet

Phenmetrazinum [INN-Latin] msds (material safety sheet)

Phenmetrazinum_[INN-Latin] MSDS

Phenmetrazinum [INN-Latin] Synthesis Reference

No information avaliable

Phenmetrazinum [INN-Latin] Molecular Weight

177.243 g/mol

Phenmetrazinum [INN-Latin] Melting Point

139 oC

Phenmetrazinum [INN-Latin] H2O Solubility

>5 mg/L

Phenmetrazinum [INN-Latin] State


Phenmetrazinum [INN-Latin] LogP


Phenmetrazinum [INN-Latin] Dosage Forms


Phenmetrazinum [INN-Latin] Indication

Used as an anorectic in the treatment of obesity.

Phenmetrazinum [INN-Latin] Pharmacology

Phenmetrazine is a sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine. Amphetamines are non-catecholamine sympathomimetic amines with CNS stimulant activity. Phenmetrazine was originally sold under the tradename Preludin as an anorectic. It has since been removed from the market. It is by some considered to have a greater potential for addiction than the amphetamines, and has been abused in many countries, for example Sweden.

Phenmetrazinum [INN-Latin] Absorption

Readily absorbed from the gastro-intestinal tract and buccal mucosa.

Phenmetrazinum [INN-Latin] side effects and Toxicity

Adult monkeys have an LD50 of 15 to 20 mg/kg, whereas for young monkeys the LD50 is only 5 mg/kg. Symptoms of overdose include acute central nervous system stimulation, cardiotoxicity causing tachycardia, arrhythmias, hypertension, and cardiovascular collapse. Whilst some patients show signs of toxicity at blood concentrations of 20 µg/L, chronic abusers of amphetamine have been known to have blood concentration of up to 3000 µg/L.

Phenmetrazinum [INN-Latin] Patient Information

No information avaliable

Phenmetrazinum [INN-Latin] Organisms Affected

Humans and other mammals