PharmacyCodes



Fenmetrazina [INN-Spanish] en es it fr

Fenmetrazina [INN-Spanish] Brand names, Fenmetrazina [INN-Spanish] Analogs

Fenmetrazina [INN-Spanish] Brand Names Mixture

  • No information avaliable

Fenmetrazina [INN-Spanish] Chemical_Formula

C11H15NO

Fenmetrazina [INN-Spanish] RX_link

No information avaliable

Fenmetrazina [INN-Spanish] fda sheet

Fenmetrazina [INN-Spanish] msds (material safety sheet)

Fenmetrazina_[INN-Spanish] MSDS

Fenmetrazina [INN-Spanish] Synthesis Reference

No information avaliable

Fenmetrazina [INN-Spanish] Molecular Weight

177.243 g/mol

Fenmetrazina [INN-Spanish] Melting Point

139 oC

Fenmetrazina [INN-Spanish] H2O Solubility

>5 mg/L

Fenmetrazina [INN-Spanish] State

Solid

Fenmetrazina [INN-Spanish] LogP

1.796

Fenmetrazina [INN-Spanish] Dosage Forms

Tablet

Fenmetrazina [INN-Spanish] Indication

Used as an anorectic in the treatment of obesity.

Fenmetrazina [INN-Spanish] Pharmacology

Phenmetrazine is a sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine. Amphetamines are non-catecholamine sympathomimetic amines with CNS stimulant activity. Phenmetrazine was originally sold under the tradename Preludin as an anorectic. It has since been removed from the market. It is by some considered to have a greater potential for addiction than the amphetamines, and has been abused in many countries, for example Sweden.

Fenmetrazina [INN-Spanish] Absorption

Readily absorbed from the gastro-intestinal tract and buccal mucosa.

Fenmetrazina [INN-Spanish] side effects and Toxicity

Adult monkeys have an LD50 of 15 to 20 mg/kg, whereas for young monkeys the LD50 is only 5 mg/kg. Symptoms of overdose include acute central nervous system stimulation, cardiotoxicity causing tachycardia, arrhythmias, hypertension, and cardiovascular collapse. Whilst some patients show signs of toxicity at blood concentrations of 20 µg/L, chronic abusers of amphetamine have been known to have blood concentration of up to 3000 µg/L.

Fenmetrazina [INN-Spanish] Patient Information

No information avaliable

Fenmetrazina [INN-Spanish] Organisms Affected

Humans and other mammals