Marsin
Brand names,
Marsin
Analogs
Marsin
Brand Names Mixture
Marsin
Chemical_Formula
C11H15NO
Marsin
RX_link
No information avaliable
Marsin
fda sheet
Marsin
msds (material safety sheet)
Marsin
Synthesis Reference
No information avaliable
Marsin
Molecular Weight
177.243 g/mol
Marsin
Melting Point
139 oC
Marsin
H2O Solubility
>5 mg/L
Marsin
State
Solid
Marsin
LogP
1.796
Marsin
Dosage Forms
Tablet
Marsin
Indication
Used as an anorectic in the treatment of obesity.
Marsin
Pharmacology
Phenmetrazine is a sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine. Amphetamines are non-catecholamine sympathomimetic amines with CNS stimulant activity. Phenmetrazine was originally sold under the tradename Preludin as an anorectic. It has since been removed from the market. It is by some considered to have a greater potential for addiction than the amphetamines, and has been abused in many countries, for example Sweden.
Marsin
Absorption
Readily absorbed from the gastro-intestinal tract and buccal mucosa.
Marsin
side effects and Toxicity
Adult monkeys have an LD50 of 15 to 20 mg/kg, whereas for young monkeys the LD50 is only 5 mg/kg. Symptoms of overdose include acute central nervous system stimulation, cardiotoxicity causing tachycardia, arrhythmias, hypertension, and cardiovascular collapse. Whilst some patients show signs of toxicity at blood concentrations of 20 µg/L, chronic abusers of amphetamine have been known to have blood concentration of up to 3000 µg/L.
Marsin
Patient Information
No information avaliable
Marsin
Organisms Affected
Humans and other mammals