Psychamine A 66 hydrochloride
Brand names,
Psychamine A 66 hydrochloride
Analogs
Psychamine A 66 hydrochloride
Brand Names Mixture
Psychamine A 66 hydrochloride
Chemical_Formula
C11H15NO
Psychamine A 66 hydrochloride
RX_link
No information avaliable
Psychamine A 66 hydrochloride
fda sheet
Psychamine A 66 hydrochloride
msds (material safety sheet)
Psychamine A 66 hydrochloride
Synthesis Reference
No information avaliable
Psychamine A 66 hydrochloride
Molecular Weight
177.243 g/mol
Psychamine A 66 hydrochloride
Melting Point
139 oC
Psychamine A 66 hydrochloride
H2O Solubility
>5 mg/L
Psychamine A 66 hydrochloride
State
Solid
Psychamine A 66 hydrochloride
LogP
1.796
Psychamine A 66 hydrochloride
Dosage Forms
Tablet
Psychamine A 66 hydrochloride
Indication
Used as an anorectic in the treatment of obesity.
Psychamine A 66 hydrochloride
Pharmacology
Phenmetrazine is a sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine. Amphetamines are non-catecholamine sympathomimetic amines with CNS stimulant activity. Phenmetrazine was originally sold under the tradename Preludin as an anorectic. It has since been removed from the market. It is by some considered to have a greater potential for addiction than the amphetamines, and has been abused in many countries, for example Sweden.
Psychamine A 66 hydrochloride
Absorption
Readily absorbed from the gastro-intestinal tract and buccal mucosa.
Psychamine A 66 hydrochloride
side effects and Toxicity
Adult monkeys have an LD50 of 15 to 20 mg/kg, whereas for young monkeys the LD50 is only 5 mg/kg. Symptoms of overdose include acute central nervous system stimulation, cardiotoxicity causing tachycardia, arrhythmias, hypertension, and cardiovascular collapse. Whilst some patients show signs of toxicity at blood concentrations of 20 µg/L, chronic abusers of amphetamine have been known to have blood concentration of up to 3000 µg/L.
Psychamine A 66 hydrochloride
Patient Information
No information avaliable
Psychamine A 66 hydrochloride
Organisms Affected
Humans and other mammals