Preludin hydrochloride
Preludin hydrochloride Brand names, Preludin hydrochloride Analogs
- 2-Phenyl-3-Methylmorpholine
- 3-Methyl-2-phenylmorpholine
- Bromadryl
- Cafilon
- Dexphenmetrazine
- Fenmetrazin
- Fenmetrazina [INN-Spanish]
- Marsin
- Mefolin
- Neo-zine
- Oxazimedrine
- Phenmetraline hydrochloride
- Phenmetrazin
- Phenmetrazine hydrochloride
- Phenmetrazinum [INN-Latin]
- Preludin
- Preludin hydrochloride
- Probese-P
- Probese-P hydrochloride
- Psychamine A 66
- Psychamine A 66 hydrochloride
- USAF Ge-1
Preludin hydrochloride Brand Names Mixture
- No information avaliable
Preludin hydrochloride Chemical_Formula
C11H15NO
Preludin hydrochloride RX_link
No information avaliable
Preludin hydrochloride fda sheet
Preludin hydrochloride msds (material safety sheet)
Preludin hydrochloride Synthesis Reference
No information avaliable
Preludin hydrochloride Molecular Weight
177.243 g/mol
Preludin hydrochloride Melting Point
139 oC
Preludin hydrochloride H2O Solubility
>5 mg/L
Preludin hydrochloride State
Solid
Preludin hydrochloride LogP
1.796
Preludin hydrochloride Dosage Forms
Tablet
Preludin hydrochloride Indication
Used as an anorectic in the treatment of obesity.
Preludin hydrochloride Pharmacology
Phenmetrazine is a sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine. Amphetamines are non-catecholamine sympathomimetic amines with CNS stimulant activity. Phenmetrazine was originally sold under the tradename Preludin as an anorectic. It has since been removed from the market. It is by some considered to have a greater potential for addiction than the amphetamines, and has been abused in many countries, for example Sweden.
Preludin hydrochloride Absorption
Readily absorbed from the gastro-intestinal tract and buccal mucosa.
Preludin hydrochloride side effects and Toxicity
Adult monkeys have an LD50 of 15 to 20 mg/kg, whereas for young monkeys the LD50 is only 5 mg/kg. Symptoms of overdose include acute central nervous system stimulation, cardiotoxicity causing tachycardia, arrhythmias, hypertension, and cardiovascular collapse. Whilst some patients show signs of toxicity at blood concentrations of 20 µg/L, chronic abusers of amphetamine have been known to have blood concentration of up to 3000 µg/L.
Preludin hydrochloride Patient Information
No information avaliable
Preludin hydrochloride Organisms Affected
Humans and other mammals
