Phenmetrazine hydrochloride
Phenmetrazine hydrochloride Brand names, Phenmetrazine hydrochloride Analogs
- 2-Phenyl-3-Methylmorpholine
- 3-Methyl-2-phenylmorpholine
- Bromadryl
- Cafilon
- Dexphenmetrazine
- Fenmetrazin
- Fenmetrazina [INN-Spanish]
- Marsin
- Mefolin
- Neo-zine
- Oxazimedrine
- Phenmetraline hydrochloride
- Phenmetrazin
- Phenmetrazine hydrochloride
- Phenmetrazinum [INN-Latin]
- Preludin
- Preludin hydrochloride
- Probese-P
- Probese-P hydrochloride
- Psychamine A 66
- Psychamine A 66 hydrochloride
- USAF Ge-1
Phenmetrazine hydrochloride Brand Names Mixture
- No information avaliable
Phenmetrazine hydrochloride Chemical_Formula
C11H15NO
Phenmetrazine hydrochloride RX_link
No information avaliable
Phenmetrazine hydrochloride fda sheet
Phenmetrazine hydrochloride msds (material safety sheet)
Phenmetrazine hydrochloride Synthesis Reference
No information avaliable
Phenmetrazine hydrochloride Molecular Weight
177.243 g/mol
Phenmetrazine hydrochloride Melting Point
139 oC
Phenmetrazine hydrochloride H2O Solubility
>5 mg/L
Phenmetrazine hydrochloride State
Solid
Phenmetrazine hydrochloride LogP
1.796
Phenmetrazine hydrochloride Dosage Forms
Tablet
Phenmetrazine hydrochloride Indication
Used as an anorectic in the treatment of obesity.
Phenmetrazine hydrochloride Pharmacology
Phenmetrazine is a sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine. Amphetamines are non-catecholamine sympathomimetic amines with CNS stimulant activity. Phenmetrazine was originally sold under the tradename Preludin as an anorectic. It has since been removed from the market. It is by some considered to have a greater potential for addiction than the amphetamines, and has been abused in many countries, for example Sweden.
Phenmetrazine hydrochloride Absorption
Readily absorbed from the gastro-intestinal tract and buccal mucosa.
Phenmetrazine hydrochloride side effects and Toxicity
Adult monkeys have an LD50 of 15 to 20 mg/kg, whereas for young monkeys the LD50 is only 5 mg/kg. Symptoms of overdose include acute central nervous system stimulation, cardiotoxicity causing tachycardia, arrhythmias, hypertension, and cardiovascular collapse. Whilst some patients show signs of toxicity at blood concentrations of 20 µg/L, chronic abusers of amphetamine have been known to have blood concentration of up to 3000 µg/L.
Phenmetrazine hydrochloride Patient Information
No information avaliable
Phenmetrazine hydrochloride Organisms Affected
Humans and other mammals
