PharmacyCodes



Phenmetrazin en es it fr

Phenmetrazin Brand names, Phenmetrazin Analogs

Phenmetrazin Brand Names Mixture

  • No information avaliable

Phenmetrazin Chemical_Formula

C11H15NO

Phenmetrazin RX_link

No information avaliable

Phenmetrazin fda sheet

Phenmetrazin msds (material safety sheet)

Phenmetrazin MSDS

Phenmetrazin Synthesis Reference

No information avaliable

Phenmetrazin Molecular Weight

177.243 g/mol

Phenmetrazin Melting Point

139 oC

Phenmetrazin H2O Solubility

>5 mg/L

Phenmetrazin State

Solid

Phenmetrazin LogP

1.796

Phenmetrazin Dosage Forms

Tablet

Phenmetrazin Indication

Used as an anorectic in the treatment of obesity.

Phenmetrazin Pharmacology

Phenmetrazine is a sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine. Amphetamines are non-catecholamine sympathomimetic amines with CNS stimulant activity. Phenmetrazine was originally sold under the tradename Preludin as an anorectic. It has since been removed from the market. It is by some considered to have a greater potential for addiction than the amphetamines, and has been abused in many countries, for example Sweden.

Phenmetrazin Absorption

Readily absorbed from the gastro-intestinal tract and buccal mucosa.

Phenmetrazin side effects and Toxicity

Adult monkeys have an LD50 of 15 to 20 mg/kg, whereas for young monkeys the LD50 is only 5 mg/kg. Symptoms of overdose include acute central nervous system stimulation, cardiotoxicity causing tachycardia, arrhythmias, hypertension, and cardiovascular collapse. Whilst some patients show signs of toxicity at blood concentrations of 20 µg/L, chronic abusers of amphetamine have been known to have blood concentration of up to 3000 µg/L.

Phenmetrazin Patient Information

No information avaliable

Phenmetrazin Organisms Affected

Humans and other mammals