Probese-P hydrochloride
Probese-P hydrochloride Brand names, Probese-P hydrochloride Analogs
- 2-Phenyl-3-Methylmorpholine
- 3-Methyl-2-phenylmorpholine
- Bromadryl
- Cafilon
- Dexphenmetrazine
- Fenmetrazin
- Fenmetrazina [INN-Spanish]
- Marsin
- Mefolin
- Neo-zine
- Oxazimedrine
- Phenmetraline hydrochloride
- Phenmetrazin
- Phenmetrazine hydrochloride
- Phenmetrazinum [INN-Latin]
- Preludin
- Preludin hydrochloride
- Probese-P
- Probese-P hydrochloride
- Psychamine A 66
- Psychamine A 66 hydrochloride
- USAF Ge-1
Probese-P hydrochloride Brand Names Mixture
- No information avaliable
Probese-P hydrochloride Chemical_Formula
C11H15NO
Probese-P hydrochloride RX_link
No information avaliable
Probese-P hydrochloride fda sheet
Probese-P hydrochloride msds (material safety sheet)
Probese-P hydrochloride Synthesis Reference
No information avaliable
Probese-P hydrochloride Molecular Weight
177.243 g/mol
Probese-P hydrochloride Melting Point
139 oC
Probese-P hydrochloride H2O Solubility
>5 mg/L
Probese-P hydrochloride State
Solid
Probese-P hydrochloride LogP
1.796
Probese-P hydrochloride Dosage Forms
Tablet
Probese-P hydrochloride Indication
Used as an anorectic in the treatment of obesity.
Probese-P hydrochloride Pharmacology
Phenmetrazine is a sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine. Amphetamines are non-catecholamine sympathomimetic amines with CNS stimulant activity. Phenmetrazine was originally sold under the tradename Preludin as an anorectic. It has since been removed from the market. It is by some considered to have a greater potential for addiction than the amphetamines, and has been abused in many countries, for example Sweden.
Probese-P hydrochloride Absorption
Readily absorbed from the gastro-intestinal tract and buccal mucosa.
Probese-P hydrochloride side effects and Toxicity
Adult monkeys have an LD50 of 15 to 20 mg/kg, whereas for young monkeys the LD50 is only 5 mg/kg. Symptoms of overdose include acute central nervous system stimulation, cardiotoxicity causing tachycardia, arrhythmias, hypertension, and cardiovascular collapse. Whilst some patients show signs of toxicity at blood concentrations of 20 µg/L, chronic abusers of amphetamine have been known to have blood concentration of up to 3000 µg/L.
Probese-P hydrochloride Patient Information
No information avaliable
Probese-P hydrochloride Organisms Affected
Humans and other mammals
