USAF Ge-1
USAF Ge-1 Brand names, USAF Ge-1 Analogs
- 2-Phenyl-3-Methylmorpholine
- 3-Methyl-2-phenylmorpholine
- Bromadryl
- Cafilon
- Dexphenmetrazine
- Fenmetrazin
- Fenmetrazina [INN-Spanish]
- Marsin
- Mefolin
- Neo-zine
- Oxazimedrine
- Phenmetraline hydrochloride
- Phenmetrazin
- Phenmetrazine hydrochloride
- Phenmetrazinum [INN-Latin]
- Preludin
- Preludin hydrochloride
- Probese-P
- Probese-P hydrochloride
- Psychamine A 66
- Psychamine A 66 hydrochloride
- USAF Ge-1
USAF Ge-1 Brand Names Mixture
- No information avaliable
USAF Ge-1 Chemical_Formula
C11H15NO
USAF Ge-1 RX_link
No information avaliable
USAF Ge-1 fda sheet
USAF Ge-1 msds (material safety sheet)
USAF Ge-1 Synthesis Reference
No information avaliable
USAF Ge-1 Molecular Weight
177.243 g/mol
USAF Ge-1 Melting Point
139 oC
USAF Ge-1 H2O Solubility
>5 mg/L
USAF Ge-1 State
Solid
USAF Ge-1 LogP
1.796
USAF Ge-1 Dosage Forms
Tablet
USAF Ge-1 Indication
Used as an anorectic in the treatment of obesity.
USAF Ge-1 Pharmacology
Phenmetrazine is a sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine. Amphetamines are non-catecholamine sympathomimetic amines with CNS stimulant activity. Phenmetrazine was originally sold under the tradename Preludin as an anorectic. It has since been removed from the market. It is by some considered to have a greater potential for addiction than the amphetamines, and has been abused in many countries, for example Sweden.
USAF Ge-1 Absorption
Readily absorbed from the gastro-intestinal tract and buccal mucosa.
USAF Ge-1 side effects and Toxicity
Adult monkeys have an LD50 of 15 to 20 mg/kg, whereas for young monkeys the LD50 is only 5 mg/kg. Symptoms of overdose include acute central nervous system stimulation, cardiotoxicity causing tachycardia, arrhythmias, hypertension, and cardiovascular collapse. Whilst some patients show signs of toxicity at blood concentrations of 20 µg/L, chronic abusers of amphetamine have been known to have blood concentration of up to 3000 µg/L.
USAF Ge-1 Patient Information
No information avaliable
USAF Ge-1 Organisms Affected
Humans and other mammals
