PharmacyCodes



Mefolin en es it fr

Mefolin Brand names, Mefolin Analogs

Mefolin Brand Names Mixture

  • No information avaliable

Mefolin Chemical_Formula

C11H15NO

Mefolin RX_link

No information avaliable

Mefolin fda sheet

Mefolin msds (material safety sheet)

Mefolin MSDS

Mefolin Synthesis Reference

No information avaliable

Mefolin Molecular Weight

177.243 g/mol

Mefolin Melting Point

139 oC

Mefolin H2O Solubility

>5 mg/L

Mefolin State

Solid

Mefolin LogP

1.796

Mefolin Dosage Forms

Tablet

Mefolin Indication

Used as an anorectic in the treatment of obesity.

Mefolin Pharmacology

Phenmetrazine is a sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine. Amphetamines are non-catecholamine sympathomimetic amines with CNS stimulant activity. Phenmetrazine was originally sold under the tradename Preludin as an anorectic. It has since been removed from the market. It is by some considered to have a greater potential for addiction than the amphetamines, and has been abused in many countries, for example Sweden.

Mefolin Absorption

Readily absorbed from the gastro-intestinal tract and buccal mucosa.

Mefolin side effects and Toxicity

Adult monkeys have an LD50 of 15 to 20 mg/kg, whereas for young monkeys the LD50 is only 5 mg/kg. Symptoms of overdose include acute central nervous system stimulation, cardiotoxicity causing tachycardia, arrhythmias, hypertension, and cardiovascular collapse. Whilst some patients show signs of toxicity at blood concentrations of 20 µg/L, chronic abusers of amphetamine have been known to have blood concentration of up to 3000 µg/L.

Mefolin Patient Information

No information avaliable

Mefolin Organisms Affected

Humans and other mammals