Aberel

Aberel Brand names, Aberel Analogs

Aberel Brand Names Mixture

No information avaliable

Aberel Chemical_Formula

C₂₀H₂₈O₂

Aberel RX_link

http://www.rxlist.com/cgi/generic/tretinoin.htm

Aberel fda sheet

Aberel FDA

Aberel msds (material safety sheet)

Aberel MSDS

Aberel Synthesis Reference

Matsui et al.; J.Vitaminol.; 4; 190, 192(1958)

Aberel Molecular Weight

300.435 g/mol

Aberel Melting Point

181 ^oC

Aberel H₂O Solubility

<0.1 g/100 mL

Aberel State

Solid

Aberel LogP

5.067

Aberel Dosage Forms

Capsule; Cream; Gel; Liquid

Aberel Indication

For the the induction of remission in patients with acute promyelocytic leukemia (APL), French-American-British (FAB) classification M3 (including the M3 variant); For the topical treatment of acne vulgaris, flat warts and other skin conditions (psoriasis, ichthyosis congenita, icthyosis vulgaris, lamellar icthyosis, keratosis palmaris et plantaris, epidermolytic hyperkeratosis, senile comedones, senile keratosis, keratosis follicularis (Darier's disease), and basal cell carcinomas.); For palliative therapy to improve fine wrinkling, mottled hyperpigmentation, roughness associated with photodamage.

Aberel Pharmacology

Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). Retinoids such as tretinoin are important regulators of cell reproduction, proliferation, and differentiation and are used to treat acne and photodamaged skin and to manage keratinization disorders such as ichthyosis and keratosis follicularis. Tretinoin also represents the class of anticancer drugs called differentiating agents and is used in the treatment of acute promyelocytic leukemia (APL).

Aberel Absorption

1-31% (topical);

Aberel side effects and Toxicity

No information avaliable

Aberel Patient Information