Vitinoin

Vitinoin Brand names, Vitinoin Analogs

Vitinoin Brand Names Mixture

No information avaliable

Vitinoin Chemical_Formula

C₂₀H₂₈O₂

Vitinoin RX_link

http://www.rxlist.com/cgi/generic/tretinoin.htm

Vitinoin fda sheet

Vitinoin FDA

Vitinoin msds (material safety sheet)

Vitinoin MSDS

Vitinoin Synthesis Reference

Matsui et al.; J.Vitaminol.; 4; 190, 192(1958)

Vitinoin Molecular Weight

300.435 g/mol

Vitinoin Melting Point

181 ^oC

Vitinoin H₂O Solubility

<0.1 g/100 mL

Vitinoin State

Solid

Vitinoin LogP

5.067

Vitinoin Dosage Forms

Capsule; Cream; Gel; Liquid

Vitinoin Indication

For the the induction of remission in patients with acute promyelocytic leukemia (APL), French-American-British (FAB) classification M3 (including the M3 variant); For the topical treatment of acne vulgaris, flat warts and other skin conditions (psoriasis, ichthyosis congenita, icthyosis vulgaris, lamellar icthyosis, keratosis palmaris et plantaris, epidermolytic hyperkeratosis, senile comedones, senile keratosis, keratosis follicularis (Darier's disease), and basal cell carcinomas.); For palliative therapy to improve fine wrinkling, mottled hyperpigmentation, roughness associated with photodamage.

Vitinoin Pharmacology

Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). Retinoids such as tretinoin are important regulators of cell reproduction, proliferation, and differentiation and are used to treat acne and photodamaged skin and to manage keratinization disorders such as ichthyosis and keratosis follicularis. Tretinoin also represents the class of anticancer drugs called differentiating agents and is used in the treatment of acute promyelocytic leukemia (APL).

Vitinoin Absorption

1-31% (topical);

Vitinoin side effects and Toxicity

No information avaliable

Vitinoin Patient Information