Stieva-a Forte
Brand names,
Stieva-a Forte
Analogs
Stieva-a Forte
Brand Names Mixture
Stieva-a Forte
Chemical_Formula
C20H28O2
Stieva-a Forte
RX_link
http://www.rxlist.com/cgi/generic/tretinoin.htm
Stieva-a Forte
fda sheet
Stieva-a Forte
msds (material safety sheet)
Stieva-a Forte
Synthesis Reference
Matsui et al.; J.Vitaminol.; 4; 190, 192(1958)
Stieva-a Forte
Molecular Weight
300.435 g/mol
Stieva-a Forte
Melting Point
181 oC
Stieva-a Forte
H2O Solubility
<0.1 g/100 mL
Stieva-a Forte
State
Solid
Stieva-a Forte
LogP
5.067
Stieva-a Forte
Dosage Forms
Capsule; Cream; Gel; Liquid
Stieva-a Forte
Indication
For the the induction of remission in patients with acute promyelocytic leukemia (APL), French-American-British (FAB) classification M3 (including the M3 variant); For the topical treatment of acne vulgaris, flat warts and other skin conditions (psoriasis, ichthyosis congenita, icthyosis vulgaris, lamellar icthyosis, keratosis palmaris et plantaris, epidermolytic hyperkeratosis, senile comedones, senile keratosis, keratosis follicularis (Darier's disease), and basal cell carcinomas.); For palliative therapy to improve fine wrinkling, mottled hyperpigmentation, roughness associated with photodamage.
Stieva-a Forte
Pharmacology
Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). Retinoids such as tretinoin are important regulators of cell reproduction, proliferation, and differentiation and are used to treat acne and photodamaged skin and to manage keratinization disorders such as ichthyosis and keratosis follicularis. Tretinoin also represents the class of anticancer drugs called differentiating agents and is used in the treatment of acute promyelocytic leukemia (APL).
Stieva-a Forte
Absorption
1-31% (topical);
Stieva-a Forte
side effects and Toxicity
No information avaliable
Stieva-a Forte
Patient Information
No information avaliable
Stieva-a Forte
Organisms Affected
Humans and other mammals