??-Retinoic Acid en es it fr

??-Retinoic Acid Brand names, ??-Retinoic Acid Analogs

??-Retinoic Acid Brand Names Mixture

  • No information avaliable

??-Retinoic Acid Chemical_Formula


??-Retinoic Acid RX_link


??-Retinoic Acid fda sheet

??-Retinoic_Acid FDA

??-Retinoic Acid msds (material safety sheet)

??-Retinoic_Acid MSDS

??-Retinoic Acid Synthesis Reference

Matsui et al.; J.Vitaminol.; 4; 190, 192(1958)

??-Retinoic Acid Molecular Weight

300.435 g/mol

??-Retinoic Acid Melting Point

181 oC

??-Retinoic Acid H2O Solubility

<0.1 g/100 mL

??-Retinoic Acid State


??-Retinoic Acid LogP


??-Retinoic Acid Dosage Forms

Capsule; Cream; Gel; Liquid

??-Retinoic Acid Indication

For the the induction of remission in patients with acute promyelocytic leukemia (APL), French-American-British (FAB) classification M3 (including the M3 variant); For the topical treatment of acne vulgaris, flat warts and other skin conditions (psoriasis, ichthyosis congenita, icthyosis vulgaris, lamellar icthyosis, keratosis palmaris et plantaris, epidermolytic hyperkeratosis, senile comedones, senile keratosis, keratosis follicularis (Darier's disease), and basal cell carcinomas.); For palliative therapy to improve fine wrinkling, mottled hyperpigmentation, roughness associated with photodamage.

??-Retinoic Acid Pharmacology

Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). Retinoids such as tretinoin are important regulators of cell reproduction, proliferation, and differentiation and are used to treat acne and photodamaged skin and to manage keratinization disorders such as ichthyosis and keratosis follicularis. Tretinoin also represents the class of anticancer drugs called differentiating agents and is used in the treatment of acute promyelocytic leukemia (APL).

??-Retinoic Acid Absorption

1-31% (topical);

??-Retinoic Acid side effects and Toxicity

No information avaliable

??-Retinoic Acid Patient Information

No information avaliable

??-Retinoic Acid Organisms Affected

Humans and other mammals