??-Retinoic Acid
??-Retinoic Acid Brand names, ??-Retinoic Acid Analogs
- Aberel
- Accutane
- Airol
- Aknefug
- Aknoten
- All Trans Retinoic Acid
- All Trans-Retinoic Acid
- Amnesteem
- Avita
- Beta-Retinoic Acid
- Claravis
- Dermairol
- Eudyna
- Isotretinoin
- Lsotretinoin
- Panretin
- Renova
- Retin-A
- Retin-a Micro
- Retinoate
- Retinoic Acid
- Retinoic Acid, All Trans Isomer
- Retionic Acid
- Retisol-A
- Solage
- Sotret
- Stieva-A
- Stieva-a Forte
- Trans-Retinoic Acid
- Tretin M
- Tri-Luma
- Vesanoid
- Vitamin a Acid
- Vitinoin
- ??-Retinoic Acid
??-Retinoic Acid Brand Names Mixture
- No information avaliable
??-Retinoic Acid Chemical_Formula
C20H28O2
??-Retinoic Acid RX_link
http://www.rxlist.com/cgi/generic/tretinoin.htm
??-Retinoic Acid fda sheet
??-Retinoic Acid msds (material safety sheet)
??-Retinoic Acid Synthesis Reference
Matsui et al.; J.Vitaminol.; 4; 190, 192(1958)
??-Retinoic Acid Molecular Weight
300.435 g/mol
??-Retinoic Acid Melting Point
181 oC
??-Retinoic Acid H2O Solubility
<0.1 g/100 mL
??-Retinoic Acid State
Solid
??-Retinoic Acid LogP
5.067
??-Retinoic Acid Dosage Forms
Capsule; Cream; Gel; Liquid
??-Retinoic Acid Indication
For the the induction of remission in patients with acute promyelocytic leukemia (APL), French-American-British (FAB) classification M3 (including the M3 variant); For the topical treatment of acne vulgaris, flat warts and other skin conditions (psoriasis, ichthyosis congenita, icthyosis vulgaris, lamellar icthyosis, keratosis palmaris et plantaris, epidermolytic hyperkeratosis, senile comedones, senile keratosis, keratosis follicularis (Darier's disease), and basal cell carcinomas.); For palliative therapy to improve fine wrinkling, mottled hyperpigmentation, roughness associated with photodamage.
??-Retinoic Acid Pharmacology
Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). Retinoids such as tretinoin are important regulators of cell reproduction, proliferation, and differentiation and are used to treat acne and photodamaged skin and to manage keratinization disorders such as ichthyosis and keratosis follicularis. Tretinoin also represents the class of anticancer drugs called differentiating agents and is used in the treatment of acute promyelocytic leukemia (APL).
??-Retinoic Acid Absorption
1-31% (topical);
??-Retinoic Acid side effects and Toxicity
No information avaliable
??-Retinoic Acid Patient Information
No information avaliable
??-Retinoic Acid Organisms Affected
Humans and other mammals
