Retionic Acid

Retionic Acid Brand names, Retionic Acid Analogs

Retionic Acid Brand Names Mixture

No information avaliable

Retionic Acid Chemical_Formula

C₂₀H₂₈O₂

Retionic Acid RX_link

http://www.rxlist.com/cgi/generic/tretinoin.htm

Retionic Acid fda sheet

Retionic_Acid FDA

Retionic Acid msds (material safety sheet)

Retionic_Acid MSDS

Retionic Acid Synthesis Reference

Matsui et al.; J.Vitaminol.; 4; 190, 192(1958)

Retionic Acid Molecular Weight

300.435 g/mol

Retionic Acid Melting Point

181 ^oC

Retionic Acid H₂O Solubility

<0.1 g/100 mL

Retionic Acid State

Solid

Retionic Acid LogP

5.067

Retionic Acid Dosage Forms

Capsule; Cream; Gel; Liquid

Retionic Acid Indication

For the the induction of remission in patients with acute promyelocytic leukemia (APL), French-American-British (FAB) classification M3 (including the M3 variant); For the topical treatment of acne vulgaris, flat warts and other skin conditions (psoriasis, ichthyosis congenita, icthyosis vulgaris, lamellar icthyosis, keratosis palmaris et plantaris, epidermolytic hyperkeratosis, senile comedones, senile keratosis, keratosis follicularis (Darier's disease), and basal cell carcinomas.); For palliative therapy to improve fine wrinkling, mottled hyperpigmentation, roughness associated with photodamage.

Retionic Acid Pharmacology

Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). Retinoids such as tretinoin are important regulators of cell reproduction, proliferation, and differentiation and are used to treat acne and photodamaged skin and to manage keratinization disorders such as ichthyosis and keratosis follicularis. Tretinoin also represents the class of anticancer drugs called differentiating agents and is used in the treatment of acute promyelocytic leukemia (APL).

Retionic Acid Absorption

1-31% (topical);

Retionic Acid side effects and Toxicity

No information avaliable

Retionic Acid Patient Information