Retisol-A

Retisol-A Brand names, Retisol-A Analogs

Retisol-A Brand Names Mixture

No information avaliable

Retisol-A Chemical_Formula

C₂₀H₂₈O₂

Retisol-A RX_link

http://www.rxlist.com/cgi/generic/tretinoin.htm

Retisol-A fda sheet

Retisol-A FDA

Retisol-A msds (material safety sheet)

Retisol-A MSDS

Retisol-A Synthesis Reference

Matsui et al.; J.Vitaminol.; 4; 190, 192(1958)

Retisol-A Molecular Weight

300.435 g/mol

Retisol-A Melting Point

181 ^oC

Retisol-A H₂O Solubility

<0.1 g/100 mL

Retisol-A State

Solid

Retisol-A LogP

5.067

Retisol-A Dosage Forms

Capsule; Cream; Gel; Liquid

Retisol-A Indication

For the the induction of remission in patients with acute promyelocytic leukemia (APL), French-American-British (FAB) classification M3 (including the M3 variant); For the topical treatment of acne vulgaris, flat warts and other skin conditions (psoriasis, ichthyosis congenita, icthyosis vulgaris, lamellar icthyosis, keratosis palmaris et plantaris, epidermolytic hyperkeratosis, senile comedones, senile keratosis, keratosis follicularis (Darier's disease), and basal cell carcinomas.); For palliative therapy to improve fine wrinkling, mottled hyperpigmentation, roughness associated with photodamage.

Retisol-A Pharmacology

Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). Retinoids such as tretinoin are important regulators of cell reproduction, proliferation, and differentiation and are used to treat acne and photodamaged skin and to manage keratinization disorders such as ichthyosis and keratosis follicularis. Tretinoin also represents the class of anticancer drugs called differentiating agents and is used in the treatment of acute promyelocytic leukemia (APL).

Retisol-A Absorption

1-31% (topical);

Retisol-A side effects and Toxicity

No information avaliable

Retisol-A Patient Information