Categorie
Ketoderm
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Ketoderm
Analogs
Ketoderm
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Ketoderm
Formule chimique
C26H28Cl2N4O4
Ketoderm
RX lien
http://www.rxlist.com/cgi/generic/ketocon.htm
Ketoderm
FDA fiche
Ketoderm
msds (fiche de securite des materiaux)
Ketoderm
Synthese de reference
J. Heeres et al., US. 4,144,346 (1979)
Ketoderm
Poids moleculaire
531.43 g/mol
Ketoderm
Point de fusion
146 oC
Ketoderm
H2O Solubilite
0,0866 mg / L
Ketoderm
Etat
Solid
Ketoderm
LogP
3.651
Ketoderm
Formes pharmaceutiques
Comprimés; Shampooing; Crème; Suspension
Ketoderm
Indication
Pour le traitement des éléments suivants infections fongiques systémiques: la candidose chronique candidose cutanéomuqueuse, muguet, candidurie, blastomycose, coccidioïdomycose, histoplasmose, chromomycose et paracoccidioidomycosis.
Ketoderm
Pharmacologie
Le kétoconazole, comme le clotrimazole, le fluconazole, itraconazole, le miconazole et le, est un agent antifongique imidazole.
Ketoderm
Absorption
Modérée
Ketoderm
Toxicite
Hépatotoxicité, DL50 = 86 mg / kg (par voie orale chez le rat)
Ketoderm
Information pour les patients
Shampoo: May be irritating to mucous membranes of the eyes and contact with this area should be
avoided.
There have been reports that use of the shampoo resulted in removal of the curl from permanently waved hair.
Tablet: Patients should be instructed to report any signs and symptoms which may suggest liver
dysfunction so that appropriate biochemical testing can be done. Such signs and symptoms may include unusual fatigue,
anorexia, nausea and/or vomiting, jaundice, dark urine or pale stools
Ketoderm
Organismes affectes
Champignons