Panfungol
Panfungol Brand names, Panfungol Analogs
Panfungol Brand Names Mixture
- No information avaliable
Panfungol Chemical_Formula
C26H28Cl2N4O4
Panfungol RX_link
http://www.rxlist.com/cgi/generic/ketocon.htm
Panfungol fda sheet
Panfungol msds (material safety sheet)
Panfungol Synthesis Reference
J. Heeres et al., U.S. Pat. 4,144,346 (1979)
Panfungol Molecular Weight
531.43 g/mol
Panfungol Melting Point
146 oC
Panfungol H2O Solubility
0.0866 mg/L
Panfungol State
Solid
Panfungol LogP
3.651
Panfungol Dosage Forms
Tablets; Shampoo; Cream; Suspension
Panfungol Indication
For the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.
Panfungol Pharmacology
Ketoconazole, like clotrimazole, fluconazole, itraconazole, and miconazole, is an imidazole antifungal agent.
Panfungol Absorption
Moderate
Panfungol side effects and Toxicity
Hepatotoxicity, LD50=86 mg/kg (orally in rat)
Panfungol Patient Information
Shampoo: May be irritating to mucous membranes of the eyes and contact with this area should be avoided.
There have been reports that use of the shampoo resulted in removal of the curl from permanently waved hair.
Tablet: Patients should be instructed to report any signs and symptoms which may suggest liver dysfunction so that appropriate biochemical testing can be done. Such signs and symptoms may include unusual fatigue, anorexia, nausea and/or vomiting, jaundice, dark urine or pale stools
Panfungol Organisms Affected
Fungi
