Ketoisdin
Ketoisdin Brand names, Ketoisdin Analogs
Ketoisdin Brand Names Mixture
- No information avaliable
Ketoisdin Chemical_Formula
C26H28Cl2N4O4
Ketoisdin RX_link
http://www.rxlist.com/cgi/generic/ketocon.htm
Ketoisdin fda sheet
Ketoisdin msds (material safety sheet)
Ketoisdin Synthesis Reference
J. Heeres et al., U.S. Pat. 4,144,346 (1979)
Ketoisdin Molecular Weight
531.43 g/mol
Ketoisdin Melting Point
146 oC
Ketoisdin H2O Solubility
0.0866 mg/L
Ketoisdin State
Solid
Ketoisdin LogP
3.651
Ketoisdin Dosage Forms
Tablets; Shampoo; Cream; Suspension
Ketoisdin Indication
For the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.
Ketoisdin Pharmacology
Ketoconazole, like clotrimazole, fluconazole, itraconazole, and miconazole, is an imidazole antifungal agent.
Ketoisdin Absorption
Moderate
Ketoisdin side effects and Toxicity
Hepatotoxicity, LD50=86 mg/kg (orally in rat)
Ketoisdin Patient Information
Shampoo: May be irritating to mucous membranes of the eyes and contact with this area should be avoided.
There have been reports that use of the shampoo resulted in removal of the curl from permanently waved hair.
Tablet: Patients should be instructed to report any signs and symptoms which may suggest liver dysfunction so that appropriate biochemical testing can be done. Such signs and symptoms may include unusual fatigue, anorexia, nausea and/or vomiting, jaundice, dark urine or pale stools
Ketoisdin Organisms Affected
Fungi
