Extina
Extina Brand names, Extina Analogs
Extina Brand Names Mixture
- No information avaliable
Extina Chemical_Formula
C26H28Cl2N4O4
Extina RX_link
http://www.rxlist.com/cgi/generic/ketocon.htm
Extina fda sheet
Extina msds (material safety sheet)
Extina Synthesis Reference
J. Heeres et al., U.S. Pat. 4,144,346 (1979)
Extina Molecular Weight
531.43 g/mol
Extina Melting Point
146 oC
Extina H2O Solubility
0.0866 mg/L
Extina State
Solid
Extina LogP
3.651
Extina Dosage Forms
Tablets; Shampoo; Cream; Suspension
Extina Indication
For the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.
Extina Pharmacology
Ketoconazole, like clotrimazole, fluconazole, itraconazole, and miconazole, is an imidazole antifungal agent.
Extina Absorption
Moderate
Extina side effects and Toxicity
Hepatotoxicity, LD50=86 mg/kg (orally in rat)
Extina Patient Information
Shampoo: May be irritating to mucous membranes of the eyes and contact with this area should be avoided.
There have been reports that use of the shampoo resulted in removal of the curl from permanently waved hair.
Tablet: Patients should be instructed to report any signs and symptoms which may suggest liver dysfunction so that appropriate biochemical testing can be done. Such signs and symptoms may include unusual fatigue, anorexia, nausea and/or vomiting, jaundice, dark urine or pale stools
Extina Organisms Affected
Fungi
