Ketozole
Ketozole Brand names, Ketozole Analogs
Ketozole Brand Names Mixture
- No information avaliable
Ketozole Chemical_Formula
C26H28Cl2N4O4
Ketozole RX_link
http://www.rxlist.com/cgi/generic/ketocon.htm
Ketozole fda sheet
Ketozole msds (material safety sheet)
Ketozole Synthesis Reference
J. Heeres et al., U.S. Pat. 4,144,346 (1979)
Ketozole Molecular Weight
531.43 g/mol
Ketozole Melting Point
146 oC
Ketozole H2O Solubility
0.0866 mg/L
Ketozole State
Solid
Ketozole LogP
3.651
Ketozole Dosage Forms
Tablets; Shampoo; Cream; Suspension
Ketozole Indication
For the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.
Ketozole Pharmacology
Ketoconazole, like clotrimazole, fluconazole, itraconazole, and miconazole, is an imidazole antifungal agent.
Ketozole Absorption
Moderate
Ketozole side effects and Toxicity
Hepatotoxicity, LD50=86 mg/kg (orally in rat)
Ketozole Patient Information
Shampoo: May be irritating to mucous membranes of the eyes and contact with this area should be avoided.
There have been reports that use of the shampoo resulted in removal of the curl from permanently waved hair.
Tablet: Patients should be instructed to report any signs and symptoms which may suggest liver dysfunction so that appropriate biochemical testing can be done. Such signs and symptoms may include unusual fatigue, anorexia, nausea and/or vomiting, jaundice, dark urine or pale stools
Ketozole Organisms Affected
Fungi
