Fungoral
Brand names,
Fungoral
Analogs
Fungoral
Brand Names Mixture
Fungoral
Chemical_Formula
C26H28Cl2N4O4
Fungoral
RX_link
http://www.rxlist.com/cgi/generic/ketocon.htm
Fungoral
fda sheet
Fungoral
msds (material safety sheet)
Fungoral
Synthesis Reference
J. Heeres et al., U.S. Pat. 4,144,346 (1979)
Fungoral
Molecular Weight
531.43 g/mol
Fungoral
Melting Point
146 oC
Fungoral
H2O Solubility
0.0866 mg/L
Fungoral
State
Solid
Fungoral
LogP
3.651
Fungoral
Dosage Forms
Tablets; Shampoo; Cream; Suspension
Fungoral
Indication
For the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.
Fungoral
Pharmacology
Ketoconazole, like clotrimazole, fluconazole, itraconazole, and miconazole, is an imidazole antifungal agent.
Fungoral
Absorption
Moderate
Fungoral
side effects and Toxicity
Hepatotoxicity, LD50=86 mg/kg (orally in rat)
Fungoral
Patient Information
Shampoo: May be irritating to mucous membranes of the eyes and contact with this area should be
avoided.
There have been reports that use of the shampoo resulted in removal of the curl from permanently waved hair.
Tablet: Patients should be instructed to report any signs and symptoms which may suggest liver
dysfunction so that appropriate biochemical testing can be done. Such signs and symptoms may include unusual fatigue,
anorexia, nausea and/or vomiting, jaundice, dark urine or pale stools
Fungoral
Organisms Affected
Fungi