Ketocanazole
Ketocanazole Brand names, Ketocanazole Analogs
Ketocanazole Brand Names Mixture
- No information avaliable
Ketocanazole Chemical_Formula
C26H28Cl2N4O4
Ketocanazole RX_link
http://www.rxlist.com/cgi/generic/ketocon.htm
Ketocanazole fda sheet
Ketocanazole msds (material safety sheet)
Ketocanazole Synthesis Reference
J. Heeres et al., U.S. Pat. 4,144,346 (1979)
Ketocanazole Molecular Weight
531.43 g/mol
Ketocanazole Melting Point
146 oC
Ketocanazole H2O Solubility
0.0866 mg/L
Ketocanazole State
Solid
Ketocanazole LogP
3.651
Ketocanazole Dosage Forms
Tablets; Shampoo; Cream; Suspension
Ketocanazole Indication
For the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.
Ketocanazole Pharmacology
Ketoconazole, like clotrimazole, fluconazole, itraconazole, and miconazole, is an imidazole antifungal agent.
Ketocanazole Absorption
Moderate
Ketocanazole side effects and Toxicity
Hepatotoxicity, LD50=86 mg/kg (orally in rat)
Ketocanazole Patient Information
Shampoo: May be irritating to mucous membranes of the eyes and contact with this area should be avoided.
There have been reports that use of the shampoo resulted in removal of the curl from permanently waved hair.
Tablet: Patients should be instructed to report any signs and symptoms which may suggest liver dysfunction so that appropriate biochemical testing can be done. Such signs and symptoms may include unusual fatigue, anorexia, nausea and/or vomiting, jaundice, dark urine or pale stools
Ketocanazole Organisms Affected
Fungi
