Ketoconazol [Inn-Spanish]

Ketoconazol [Inn-Spanish] Brand names, Ketoconazol [Inn-Spanish] Analogs

Ketoconazol [Inn-Spanish] Brand Names Mixture

No information avaliable

Ketoconazol [Inn-Spanish] Chemical_Formula

C₂₆H₂₈Cl₂N₄O₄

Ketoconazol [Inn-Spanish] RX_link

http://www.rxlist.com/cgi/generic/ketocon.htm

Ketoconazol [Inn-Spanish] fda sheet

Ketoconazol_[Inn-Spanish] FDA

Ketoconazol [Inn-Spanish] msds (material safety sheet)

Ketoconazol_[Inn-Spanish] MSDS

Ketoconazol [Inn-Spanish] Synthesis Reference

J. Heeres et al., U.S. Pat. 4,144,346 (1979)

Ketoconazol [Inn-Spanish] Molecular Weight

531.43 g/mol

Ketoconazol [Inn-Spanish] Melting Point

146 ^oC

Ketoconazol [Inn-Spanish] H₂O Solubility

0.0866 mg/L

Ketoconazol [Inn-Spanish] State

Solid

Ketoconazol [Inn-Spanish] LogP

3.651

Ketoconazol [Inn-Spanish] Dosage Forms

Tablets; Shampoo; Cream; Suspension

Ketoconazol [Inn-Spanish] Indication

For the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.

Ketoconazol [Inn-Spanish] Pharmacology

Ketoconazole, like clotrimazole, fluconazole, itraconazole, and miconazole, is an imidazole antifungal agent.

Ketoconazol [Inn-Spanish] Absorption

Moderate

Ketoconazol [Inn-Spanish] side effects and Toxicity

Hepatotoxicity, LD₅₀=86 mg/kg (orally in rat)

Ketoconazol [Inn-Spanish] Patient Information

Shampoo: May be irritating to mucous membranes of the eyes and contact with this area should be avoided.

There have been reports that use of the shampoo resulted in removal of the curl from permanently waved hair.

Tablet: Patients should be instructed to report any signs and symptoms which may suggest liver dysfunction so that appropriate biochemical testing can be done. Such signs and symptoms may include unusual fatigue, anorexia, nausea and/or vomiting, jaundice, dark urine or pale stools

Ketoconazol [Inn-Spanish] Organisms Affected

Fungi