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Orifungal Brand names, Orifungal Analogs

Orifungal Brand Names Mixture

  • No information avaliable

Orifungal Chemical_Formula


Orifungal RX_link


Orifungal fda sheet

Orifungal FDA

Orifungal msds (material safety sheet)

Orifungal MSDS

Orifungal Synthesis Reference

J. Heeres et al., U.S. Pat. 4,144,346 (1979)

Orifungal Molecular Weight

531.43 g/mol

Orifungal Melting Point

146 oC

Orifungal H2O Solubility

0.0866 mg/L

Orifungal State


Orifungal LogP


Orifungal Dosage Forms

Tablets; Shampoo; Cream; Suspension

Orifungal Indication

For the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.

Orifungal Pharmacology

Ketoconazole, like clotrimazole, fluconazole, itraconazole, and miconazole, is an imidazole antifungal agent.

Orifungal Absorption


Orifungal side effects and Toxicity

Hepatotoxicity, LD50=86 mg/kg (orally in rat)

Orifungal Patient Information

Shampoo: May be irritating to mucous membranes of the eyes and contact with this area should be avoided.

There have been reports that use of the shampoo resulted in removal of the curl from permanently waved hair.

Tablet: Patients should be instructed to report any signs and symptoms which may suggest liver dysfunction so that appropriate biochemical testing can be done. Such signs and symptoms may include unusual fatigue, anorexia, nausea and/or vomiting, jaundice, dark urine or pale stools

Orifungal Organisms Affected