Ketoderm
Ketoderm Brand names, Ketoderm Analogs
Ketoderm Brand Names Mixture
- No information avaliable
Ketoderm Chemical_Formula
C26H28Cl2N4O4
Ketoderm RX_link
http://www.rxlist.com/cgi/generic/ketocon.htm
Ketoderm fda sheet
Ketoderm msds (material safety sheet)
Ketoderm Synthesis Reference
J. Heeres et al., U.S. Pat. 4,144,346 (1979)
Ketoderm Molecular Weight
531.43 g/mol
Ketoderm Melting Point
146 oC
Ketoderm H2O Solubility
0.0866 mg/L
Ketoderm State
Solid
Ketoderm LogP
3.651
Ketoderm Dosage Forms
Tablets; Shampoo; Cream; Suspension
Ketoderm Indication
For the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.
Ketoderm Pharmacology
Ketoconazole, like clotrimazole, fluconazole, itraconazole, and miconazole, is an imidazole antifungal agent.
Ketoderm Absorption
Moderate
Ketoderm side effects and Toxicity
Hepatotoxicity, LD50=86 mg/kg (orally in rat)
Ketoderm Patient Information
Shampoo: May be irritating to mucous membranes of the eyes and contact with this area should be avoided.
There have been reports that use of the shampoo resulted in removal of the curl from permanently waved hair.
Tablet: Patients should be instructed to report any signs and symptoms which may suggest liver dysfunction so that appropriate biochemical testing can be done. Such signs and symptoms may include unusual fatigue, anorexia, nausea and/or vomiting, jaundice, dark urine or pale stools
Ketoderm Organisms Affected
Fungi
