Categorie
Ketoconazole
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Ketoconazole
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Ketoconazole
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Ketoconazole
Formule chimique
C26H28Cl2N4O4
Ketoconazole
RX lien
http://www.rxlist.com/cgi/generic/ketocon.htm
Ketoconazole
FDA fiche
Ketoconazole
msds (fiche de securite des materiaux)
Ketoconazole
Synthese de reference
J. Heeres et al., US. 4,144,346 (1979)
Ketoconazole
Poids moleculaire
531.43 g/mol
Ketoconazole
Point de fusion
146 oC
Ketoconazole
H2O Solubilite
0,0866 mg / L
Ketoconazole
Etat
Solid
Ketoconazole
LogP
3.651
Ketoconazole
Formes pharmaceutiques
Comprimés; Shampooing; Crème; Suspension
Ketoconazole
Indication
Pour le traitement des éléments suivants infections fongiques systémiques: la candidose chronique candidose cutanéomuqueuse, muguet, candidurie, blastomycose, coccidioïdomycose, histoplasmose, chromomycose et paracoccidioidomycosis.
Ketoconazole
Pharmacologie
Le kétoconazole, comme le clotrimazole, le fluconazole, itraconazole, le miconazole et le, est un agent antifongique imidazole.
Ketoconazole
Absorption
Modérée
Ketoconazole
Toxicite
Hépatotoxicité, DL50 = 86 mg / kg (par voie orale chez le rat)
Ketoconazole
Information pour les patients
Shampoo: May be irritating to mucous membranes of the eyes and contact with this area should be
avoided.
There have been reports that use of the shampoo resulted in removal of the curl from permanently waved hair.
Tablet: Patients should be instructed to report any signs and symptoms which may suggest liver
dysfunction so that appropriate biochemical testing can be done. Such signs and symptoms may include unusual fatigue,
anorexia, nausea and/or vomiting, jaundice, dark urine or pale stools
Ketoconazole
Organismes affectes
Champignons